Ivabradine (By mouth)
Treats heart failure.
CorlanorThere may be other brand names for this medicine.
When This Medicine Should Not Be Used:This medicine is not right for everyone. Do not use it if you had an allergic reaction to ivabradine, if you are pregnant, or if you have a worsened heart failure, very low blood pressure, slow heartbeat, heart block, or a pacemaker.
How to Use This Medicine:
- Your doctor will tell you how much medicine to use. Do not use more than directed.
- It is best to take this medicine with food or milk.
- Oral liquid: If you cannot swallow the tablet, you may use the oral liquid. To use:
- Empty the contents of the ampule into a medication cup. Keep the ampule in its unopened foil pouch until you are ready to use it.
- Measure the liquid with a marked oral syringe to get your dose.
- Place the tip of the oral syringe into your or your child's mouth and towards the cheek. Then slowly push down on the plunger until the oral syringe is empty.
- Do not save or reuse any leftover oral liquid in the cup or oral syringe.
- This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
- Missed dose: If you miss or spit out a dose of this medicine, skip the missed or spit out dose and go back to your regular dosing schedule.
- Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Throw away any unused oral liquid.
Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Do not use this medicine if you are also using clarithromycin, itraconazole, nefazodone, nelfinavir, or telithromycin.
- Some foods and medicine can affect how ivabradine works. Tell your doctor if you are using any of the following:
- Amiodarone, digoxin, diltiazem, phenobarbital, phenytoin, rifampicin, St John's wort, verapamil
- Beta-blocker medicine
- Do not eat grapefruit or drink grapefruit juice while you are using this medicine.
Warnings While Using This Medicine:
- It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
- Do not breastfeed during treatment with this medicine.
- Tell your doctor if you have liver disease, heart disease, low blood pressure, or heart rhythm problems.
- This medicine may increase your risk for heart rhythm problems, including atrial fibrillation (uneven heartbeat) and bradycardia (slow heartbeat).
- This medicine may cause vision changes, including temporary brightness in part of your field of vision, usually within the first 2 months of treatment. Be careful when you use machines or drive a car, especially when driving at night.
- Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Chest pain, trouble breathing
- Fainting, dizziness, or lightheadedness
- Fast, slow, pounding, or uneven heartbeat
- Unusual tiredness or weakness
If you notice these less serious side effects, talk with your doctor:
- Temporary brightness in part of your vision field
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
Last Updated: 6/10/2021