Bone biopsy; Biopsy - bone
A bone lesion biopsy is the removal of a piece of bone or bone marrow for examination.
The test is done in the following way:
Bone biopsy may also be done under general anesthesia to remove a larger sample. Then surgery to remove the bone can be done if the biopsy exam shows that there is an abnormal growth or cancer.
Follow your provider's instructions on how to prepare. This may include not eating and drinking for several hours before the procedure.
With a needle biopsy, you may feel some discomfort and pressure, even though a local anesthetic is used. You must remain still during the procedure.
After the biopsy, the area may be sore or tender for several days.
The most common reasons for bone lesion biopsy are to tell the difference between cancerous and noncancerous bone tumors and to identify other bone or bone marrow problems. It may be performed on people with bone pain and tenderness, particularly if x-ray, CT scan, or other testing reveals a problem.
No abnormal bone tissue is found.
An abnormal result may be any of the following problems.
Benign (noncancerous) bone tumors, such as:
Cancerous tumors, such as:
Abnormal results may also be due to:
Risks of this procedure may include:
A serious risk of this procedure is bone infection. Signs include:
If you have any of these signs, contact your provider right away.
People with bone disorders who also have blood clotting disorders may have an increased risk of bleeding.
Katsanos K, Sabharwal T, Cazzato RL, Gangi A. Skeletal interventions. In: Adam A, Dixon AK, Gillard JH, Schaefer-Prokop CM, eds. Grainger & Allison's Diagnostic Radiology. 7th ed. Philadelphia, PA: Elsevier; 2021:chap 87.
Schwartz HS, Holt GE, Halpern JL. Bone tumors. In: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. Sabiston Textbook of Surgery. 20th ed. Philadelphia, PA: Elsevier; 2017:chap 32.
Reisinger C, Mallinson PI, Chou H, Munk PL, Ouellette HA. Interventional radiologic techniques in management of bone tumors. In: Heymann D, ed. Bone Cancer. 2nd ed. Waltham, MA: Elsevier Academic Press; 2015:chap 44.BACK TO TOP
Review Date: 7/25/2020
Reviewed By: C. Benjamin Ma, MD, Professor, Chief, Sports Medicine and Shoulder Service, UCSF Department of Orthopaedic Surgery, San Francisco, CA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
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