Biopsy - endometrium
Endometrial biopsy is the removal of a small piece of tissue from the lining of the uterus (endometrium) for examination.
This procedure may be done with or without anesthesia. This is medicine that allows you to sleep during the procedure.
Before the test:
The instruments may feel cold. You may feel some cramping when the cervix is grasped. You may have some mild cramping as the instruments enter the uterus and the sample is collected. The discomfort is mild, though for some women it can be severe. However, the duration of the test and the pain are short.
The test is done to find the cause of:
The biopsy is normal if the cells in the sample are not abnormal.
Abnormal menstrual periods may be caused by:
Other conditions under which the test may be performed:
Risks for endometrial biopsy include:
Beard JM, Osborn J. Common office procedures. In: Rakel RE, Rakel DP, eds. Textbook of Family Medicine. 9th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 28.
Soliman PT, Lu KH. Malignant diseases of the uterus: endometrial hyperplasia, endometrial carcinoma, sarcoma: diagnosis and management. In: Gershenson DM, Lentz GM, Valea FA, Lobo RA, eds. Comprehensive Gynecology. 8th ed. Philadelphia, PA: Elsevier; 2022:chap 32.BACK TO TOP
Review Date: 7/13/2021
Reviewed By: John D. Jacobson, MD, Department of Obstetrics and Gynecology, Loma Linda University School of Medicine, Loma Linda, CA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
Health Content Provider
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- 2023 A.D.A.M., a business unit of Ebix, Inc. Any duplication or distribution of the information contained herein is strictly prohibited.