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Gallbladder radionuclide scan

Radionuclide - gallbladder; Gallbladder scan; Biliary scan; Cholescintigraphy; HIDA; Hepatobiliary nuclear imaging scan

Gallbladder radionuclide scan is a test that uses radioactive material to check gallbladder function. It is also used to look for bile duct blockage or leak.

Images

Gallbladder
Gallbladder radionuclide scan

How the Test is Performed

The health care provider will inject a radioactive chemical called a gamma emitting tracer into a vein. This material collects mostly in the liver. It will then flow with bile into the gallbladder and then to the duodenum or small intestine.

For the test:

If the provider cannot see the gallbladder after certain amount of time, you may be given a small amount of morphine. This can help the radioactive material get into the gallbladder. The morphine may cause you to feel tired after the exam.

In some cases, you may be given a medicine during this test to see how well your gallbladder squeezes (contracts). The medicine may be injected into the vein. Otherwise, you may be asked to drink a high-density drink like Boost which will help your gallbladder contract.

How to Prepare for the Test

You need to eat something within a day of the test. However, you must stop eating or drinking 4 hours before the test starts.

How the Test will Feel

You will feel a sharp prick from the needle when the tracer is injected into the vein. The site may be sore after the injection. There is normally no pain during the scan.

Why the Test is Performed

This test is very good for detecting a sudden infection of the gallbladder or blockage of a bile duct. It is also helpful in determining whether there is complication of a transplanted liver or a leak after the gallbladder has been surgically removed.

The test can also be used to detect long-term gallbladder problems.

What Abnormal Results Mean

Abnormal results may be due to:

Risks

There is a small risk to pregnant or nursing mothers. Unless it is absolutely necessary, the scan will be delayed until you are no longer pregnant or nursing.

The amount of radiation is small (less than that of a regular x-ray). It is almost all gone from the body within 1 or 2 days. Your risk from radiation may increase if you have a lot of scans.

Considerations

Most of the time, this test is done only if a person has sudden pain that may be from gallbladder disease or gallstones. For this reason, some people may need urgent treatment based on the test results.

This test is combined with other imaging (such as CT or ultrasound). After the gallbladder scan, the person may be prepared for surgery, if needed.

Related Information

Bile
Acute
Acute cholecystitis
Gallstones
Bile duct obstruction
Cyst
Transplant rejection
Liver transplant
Liver disease
Liver cancer - hepatocellular carcinoma

References

Chernecky CC, Berger BJ. Hepatobiliary scan (HIDA Scan) - diagnostic. In: Chernecky CC, Berger BJ, eds. Laboratory Tests and Diagnostic Procedures. 6th ed. Philadelphia, PA: Elsevier Saunders; 2013:635-636.

Fogel EL, Sherman S. Diseases of the gallbladder and bile ducts. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 155.

Grajo JR. Imaging of the liver. In: Sahani DV, Samir AE, eds. Abdominal Imaging. 2nd ed. Philadelphia, PA: Elsevier; 2017:chap 35.

Wang DQH, Afdhal NH. Gallstone disease. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 10th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 65.

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Review Date: 12/23/2018  

Reviewed By: Jason Levy, MD, Northside Radiology Associates, Atlanta, GA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

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