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Vitamin E

Alpha-tocopherol; Gamma-tocopherol

Vitamin E is a fat-soluble vitamin. Your body stores vitamin E in fatty tissue and the liver.

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Vitamin E benefit
Vitamin E source
Vitamin E and heart disease

Function

Vitamin E has the following functions:

Whether vitamin E can prevent cancer, heart disease, dementia, liver disease, and stroke still requires further research.

Food Sources

The best way to get the daily requirement of vitamin E is by eating food sources. Vitamin E is found in the following foods:

Fortified means that vitamins have been added to the food. Check the Nutrition Fact Panel on the food label.

Products made from these foods, such as margarine, also contain vitamin E.

Side Effects

Eating vitamin E in foods is not risky or harmful. However, high doses of vitamin E supplements (alpha-tocopherol supplements) might increase the risk of bleeding in the brain (hemorrhagic stroke).

High levels of vitamin E may also increase the risk for birth defects. However, it needs more research.

Low intake may lead to hemolytic anemia in premature babies.

Recommendations

Recommendations for vitamin E, as well as other nutrients, are provided in the Dietary Reference Intakes (DRIs) developed by the Food and Nutrition Board at the National Academies of Sciences, Engineering, and Medicine. DRI is a term for a set of reference intakes that are used to plan and assess the nutrient intakes of healthy people. These values, which vary by age and sex, include:

Recommended Dietary Allowance (RDA): The average daily level of intake that is enough to meet the nutrient needs of nearly all (97% to 98%) healthy people. An RDA is an intake level based on scientific research evidence.

Adequate Intake (AI): This level is established when there is not enough scientific research evidence to develop an RDA. It is set at a level that is thought to ensure enough nutrition.

Dietary reference intakes for vitamin E:

Infants (AI)

Children (RDA)

Adolescents and adults (RDA)

Ask your health care provider which amount is best for you.

The highest safe level of vitamin E supplements for adults is 1,500 IU/day for natural forms of vitamin E, and 1,100 IU/day for the man-made (synthetic) form.

Related Information

Vitamin K

References

Markell M, Siddiqi HA. Vitamins and trace elements. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Philadelphia, PA: Elsevier; 2022:chap 27.

Mason JB, Booth SL. Vitamins, trace minerals, and other micronutrients. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 205. 

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Review Date: 3/11/2021  

Reviewed By: Meagan Bridges, RD, University of Virginia Health System, Charlottesville, VA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. Editorial update 09/29/2021.

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