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Thrombophlebitis

Phlebitis; Deep vein thrombosis - thrombophlebitis; Thrombophilia - thrombophlebitis

Thrombophlebitis is swelling (inflammation) of a vein. A blood clot (thrombus) in the vein is the most common cause of this swelling.

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Deep venous thrombosis - iliofemoral
Venous blood clot

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Causes

Thrombophlebitis may affect deeper, larger veins or veins near the skin surface. Most of the time, it occurs in the pelvis and legs.

Blood clots may form when something slows or changes the flow of blood in the veins. Risk factors include:

Blood is more likely to clot in someone who has certain problems or disorders, such as:

Symptoms

Thrombophlebitis often causes the following symptoms:

Exams and Tests

The health care provider can often diagnose the condition based on how the affected area looks. Your provider will frequently check your vital signs. This is to make sure you don't have complications.

If the cause cannot be easily identified, one or more of the following tests may be done:

Treatment

Support stockings and wraps can help to reduce discomfort. Your provider may prescribe medicines such as:

You may be told to do the following:

Rare treatment options are:

Outlook (Prognosis)

Prompt treatment can treat thrombophlebitis and its other forms.

Possible Complications

Complications of thrombophlebitis include:

When to Contact a Medical Professional

Contact your provider if you have symptoms of thrombophlebitis.

Contact your provider right away if:

Prevention

Routine changing of intravenous (IV) lines helps to prevent thrombophlebitis related to IVs.

If you are taking a long car or plane trip:

If you are hospitalized, your provider may prescribe medicine to prevent thrombophlebitis.

Related Information

Blood clots
Superficial thrombophlebitis
Deep vein thrombosis
Lymphangitis

References

Wasan S. Superficial thrombophlebitis and its management. In: Sidawy AN, Perler BA, eds. Rutherford's Vascular Surgery and Endovascular Therapy. 10th ed. Philadelphia, PA: Elsevier; 2023:chap 151.

Weitz JI, Eikelboom JW. Venous thrombosis and embolism. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 68.

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Review Date: 2/8/2024  

Reviewed By: Linda J. Vorvick, MD, Clinical Professor, Department of Family Medicine, UW Medicine, School of Medicine, University of Washington, Seattle, WA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

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