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Distal median nerve dysfunction

Neuropathy - distal median nerve

Distal median nerve dysfunction is a form of peripheral neuropathy that affects the movement of or sensation in the hands.

A common type of distal median nerve dysfunction is carpal tunnel syndrome.

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Compression of the median nerve

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Causes

Dysfunction of one nerve group, such as the distal median nerve, is called a mononeuropathy. Mononeuropathy usually means there is a local cause of the nerve damage. Diseases affecting the entire body (systemic disorders) can also cause isolated nerve damage.

This condition occurs when the nerve is inflamed, trapped, or injured by trauma. The most common reason is trapping (entrapment) by a ligament in the wrist. Trapping puts pressure on the nerve where it passes through a narrow area. Wrist fractures may injure the median nerve directly. Or, it may increase the risk for trapping the nerve later on.

Inflammation of the tendons (tendonitis) or joints (arthritis) can also put pressure on the nerve. Some repetitive movements increase the chance of developing carpal tunnel entrapment. Women are more affected than men.

Problems that affect the tissue near the nerve or cause deposits to form in the tissue can block blood flow and lead to pressure on the nerve. Such conditions include:

In some cases, no cause can be found. Diabetes can make this condition worse.

Symptoms

Symptoms may include any of the following:

Exams and Tests

Your health care provider will examine your wrist and ask about your medical history. Tests that may be done include:

Treatment

Treatment is aimed at the underlying cause.

If the median nerve is affected by carpal tunnel syndrome, a wrist splint can reduce further injury to the nerve and help relieve symptoms. Wearing the splint at night rests the area and decreases inflammation. An injection into the wrist may help with symptoms, but it won't fix the underlying problem. Surgery may be needed if a splint or medicines don't help. Using proper ergonomics at work is essential. For example, you should use proper wrist support if you use a keyboard and mouse for computer work.

For other causes, treatment may involve any of the following:

Outlook (Prognosis)

If the cause of the nerve dysfunction can be identified and treated, there is a good chance of full recovery. In some cases, there is some or complete loss of movement or sensation. Nerve pain may be severe and persist for a long time.

Possible Complications

Complications may include:

When to Contact a Medical Professional

Call your provider if you have symptoms of distal median nerve dysfunction. Early diagnosis and treatment increase the chance of curing or controlling symptoms.

Prevention

Prevention varies, depending on the cause. In people with diabetes, controlling blood sugar may reduce the risk of developing nerve disorders.

For people with jobs that involve repetitive wrist movements, a change in the way the job is performed may be needed. Frequent breaks in activity may also help.

Related Information

Peripheral neuropathy
Distal
Carpal tunnel syndrome
Mononeuropathy
Systemic
Multiple mononeuropathy
Tendinitis
Arthritis
Multiple myeloma
Acromegaly
Hypothyroidism
Peripheral

References

Craig A. Neuropathies. In: Cifu DX, ed. Braddom's Physical Medicine and Rehabilitation. 6th ed. Philadelphia, PA: Elsevier; 2021:chap 41.

Katirji B. Disorders of peripheral nerves. In: Jankovic J, Mazziotta JC, Pomeroy SL, Newman NJ, eds. Bradley and Daroff's Neurology in Clinical Practice. 8th ed. Philadelphia, PA: Elsevier; 2022:chap 106.

Toussaint CP, Kvint S, Ali ZS, Zager EL. Distal entrapment syndromes: carpal tunnel, cubital tunnel, peroneal, and tarsal tunnel. In: Winn HR, ed. Youmans and Winn Neurological Surgery. 8th ed. Philadelphia, PA: Elsevier; 2023:chap 276.

Waldman SD. Carpal tunnel syndrome. In: Waldman SD, ed. Atlas of Common Pain Syndromes. 4th ed. Philadelphia, PA: Elsevier; 2019:chap 50.

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Review Date: 4/25/2022  

Reviewed By: Joseph V. Campellone, MD, Department of Neurology, Cooper University Hospital, Camden, NJ. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

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