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Bone marrow transplant - discharge

Transplant - bone marrow - discharge; Stem cell transplant - discharge; Hematopoietic stem cell transplant - discharge; Reduced intensity; Non-myeloablative transplant - discharge; Mini transplant - discharge; Allogenic bone marrow transplant - discharge; Autologous bone marrow transplant - discharge; Umbilical cord blood transplant - discharge

You have had a bone marrow transplant. A bone marrow transplant is a procedure to replace damaged or destroyed bone marrow with healthy bone marrow stem cells.

What to Expect at Home

It will take 6 months or more for your blood counts and immune system to fully recover. During this time, your risk for infection, bleeding, and skin problems is higher.

Your body is still weak. It may take up to a year to feel like you did before your transplant. You will likely get tired very easily. You may also have a poor appetite.

If you received bone marrow from someone else, you may develop signs of graft-versus-host disease (GVHD). Ask your health care provider to tell you what signs of GVHD you should watch for.

Mouth Care

Take good care of your mouth. Dry mouth or sores from medicines you need to take for the bone marrow transplant can lead to an increase in bacteria in your mouth. The bacteria can cause mouth infections, which can spread to other parts of your body.

Rinse your mouth 4 times a day with a salt and baking soda solution. (Mix one half teaspoon, or 2.5 grams, of salt and one half teaspoon or 2.5 grams, of baking soda in 8 ounces or 240 milliliters of water.)

Your provider may prescribe a mouth rinse. Do not use mouth rinses with alcohol in them.

Use your regular lip care products to keep your lips from drying and cracking. Tell your provider if you develop new mouth sores or pain.

Avoid foods and drinks that have a lot of sugar in them. Chew sugarless gums or suck on sugar-free popsicles or sugar-free hard candies.

Take care of your dentures, braces, or other dental products.

Preventing Infections

Take care not to get infections for up to 1 year or more after your transplant.

Practice safe eating and drinking during cancer treatment.

Wash your hands with soap and water often, including:

Keep your house clean. Stay away from crowds. Ask visitors who have a cold to wear a mask, or not to visit. Do not do yard work or handle flowers and plants.

Be careful with pets and animals.

Ask your provider what vaccines you may need and when to get them.

Other Self-care

Other things you can do to stay healthy include:

Follow-up

You will need close follow-up care from your transplant team for at least 3 months. Be sure to keep all your appointments.

When to Call the Doctor

Contact your provider if you have any of these symptoms:

Related Information

Bone marrow transplant
Chronic lymphocytic leukemia (CLL)
Acute lymphoblastic leukemia (ALL)
Acute myeloid leukemia - adult
Aplastic anemia
Chronic myelogenous leukemia (CML)
Hodgkin lymphoma
Non-Hodgkin lymphoma
Multiple myeloma
Graft-versus-host disease
Bleeding during cancer treatment
Dry mouth during cancer treatment
Eating extra calories when sick - children
Eating extra calories when sick - adults
Oral mucositis - self-care
Safe eating during cancer treatment
Drinking water safely during cancer treatment
Central venous catheter - dressing change
Central venous catheter - flushing
Peripherally inserted central catheter - flushing
Diarrhea - what to ask your health care provider - adult
Diarrhea - what to ask your doctor - child

References

Chhabra S, Hamadani M, Hari PN. Indications, outcomes, and donor selection for allogeneic hematopoietic cell transplantation for hematologic malignancies in adults. In: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Basic Principles and Practice. 8th ed. Philadelphia, PA: Elsevier; 2023:chap 103.

Im A, Pavletic SZ. Hematopoietic stem cell transplantation. In: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6th ed. Philadelphia, PA: Elsevier; 2020:chap 28.

National Comprehensive Cancer Network website. NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) Hematopoietic cell transplantation (HCT). Version 1. 2024. www.nccn.org/professionals/physician_gls/pdf/hct.pdf. Updated April 26, 2024. Accessed May 28, 2024.

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Review Date: 3/31/2024  

Reviewed By: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

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