Serial beta HCG; Repeat quantitative beta HCG; Human chorionic gonadotropin blood test - quantitative; Beta-HCG blood test - quantitative; Pregnancy test - blood - quantitative
A quantitative human chorionic gonadotropin (HCG) test measures the specific level of HCG in the blood. HCG is a hormone produced in the body during pregnancy.
Other HCG tests include:
A blood sample is needed. This is most often taken from a vein. The procedure is called a venipuncture.
No special preparation is needed.
When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging sensation. Afterward, there may be some throbbing.
HCG appears in the blood and urine of pregnant women as early as 10 days after conception. Quantitative HCG measurement helps determine the exact age of the fetus. It can also assist in the diagnosis of abnormal pregnancies, such as ectopic pregnancies, molar pregnancies, and possible miscarriages. It is also used as part of a screening test for Down syndrome.
This test is also done to diagnose abnormal conditions not related to pregnancy that can raise HCG level.
Results are given in milli-international units per milliliter (mUI/mL).
Normal levels are found in:
In pregnancy, HCG level rises rapidly during the first trimester and then declines slightly. The expected HCG ranges in pregnant women are based on the length of the pregnancy.
Normal value ranges may vary slightly among different laboratories. Talk to your provider about the meaning of your specific test result.
Higher than normal level may indicate:
During pregnancy, lower than normal levels based on the gestational age may indicate:
Risks of having blood drawn are slight, but may include:
Jain S, Pincus MR, Bluth MH, McPherson RA, Bowne WB, Lee P. Diagnosis and management of cancer using serological and other body fluid markers. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 23rd ed. St Louis, MO: Elsevier; 2017:chap 74.
Jeelani R, Bluth MH. Reproductive function and pregnancy. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 23rd ed. St Louis, MO: Elsevier; 2017:chap 25.
University of Iowa Diagnostic Laboratories. Test directory: HCG - serum, quantitative. www.healthcare.uiowa.edu/path_handbook/rhandbook/test446.html. Updated February 10, 2022. Accessed March 11, 2022.
Yarbrough ML, Stout M, Gronowski AM. Pregnancy and its disorders. In: Rifai N, ed. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. 6th ed. St Louis, MO: Elsevier; 2018:chap 69.BACK TO TOP
Review Date: 12/3/2020
Reviewed By: LaQuita Martinez, MD, Department of Obstetrics and Gynecology, Emory Johns Creek Hospital, Alpharetta, GA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. Editorial update 03/11/2022.
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