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Malaise

General ill feeling

Malaise is a general feeling of discomfort, illness, or lack of well-being.

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Considerations

Malaise is a symptom that can occur with almost any health condition. It may start slowly or quickly, depending on the type of disease.

Fatigue (feeling tired) occurs with malaise in many diseases. You can have a feeling of not having enough energy to do your usual activities.

Causes

The following lists give examples of the diseases, conditions, and medicines that can cause malaise.

SHORT-TERM (ACUTE) INFECTIOUS DISEASE

LONG-TERM (CHRONIC) INFECTIOUS DISEASE

HEART AND LUNG (CARDIOPULMONARY) DISEASE

ORGAN FAILURE

CONNECTIVE TISSUE DISEASE

ENDOCRINE or METABOLIC DISEASE

CANCER

BLOOD DISORDERS

PSYCHIATRIC

MEDICINES

Home Care

Contact your health care provider right away if you have severe malaise.

When to Contact a Medical Professional

Contact your provider if:

What to Expect at Your Office Visit

Your provider will perform a physical exam and ask questions such as:

You may have tests to confirm the diagnosis if your provider thinks the problem may be due to an illness. These may include blood tests, x-rays, or other diagnostic tests.

Your provider will recommend treatment if needed based on your exam and tests.

Related Information

Endocrine glands
Fatigue

References

Leggett JE. Approach to fever or suspected infection in the normal host. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 264.

Nield LS, Kamat D. Fever. In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Textbook of Pediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020:chap 201.

Simel DL. Approach to the patient: history and physical examination. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 6.

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Review Date: 2/2/2023  

Reviewed By: Linda J. Vorvick, MD, Clinical Professor, Department of Family Medicine, UW Medicine, School of Medicine, University of Washington, Seattle, WA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

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