CMV - congenital; Congenital CMV; Cytomegalovirus - congenital
Congenital cytomegalovirus is a condition that can occur when an infant is infected with a virus called cytomegalovirus (CMV) before birth. Congenital means the condition is present at birth.
Congenital cytomegalovirus occurs when an infected mother passes CMV to the fetus through the placenta. The mother may not have symptoms, so she may be unaware that she has CMV.
Most children infected with CMV at birth do not have symptoms. Those who do have symptoms may have:
During the exam, the health care provider may find:
There is no specific treatment for congenital CMV. Treatments focus on specific problems, such as physical therapy and appropriate education for children with delayed physical movements.
Treatment with antiviral medicines is often used for infants with neurologic (nervous system) symptoms. This treatment may reduce hearing loss later in the child's life.
Most infants who have symptoms of their infection at birth will have neurologic abnormalities later in life. Most infants without symptoms at birth will NOT have these problems.
Some children may die while they are still an infant.
Complications may include:
Have your baby checked right away if a provider did not examine your baby shortly after birth, and you suspect your baby has:
If your baby has congenital CMV, it is important to follow your provider's recommendations for well-baby examinations. That way, any growth and development problems can be identified early and treated promptly.
Cytomegalovirus is almost everywhere in the environment. The US Centers for Disease Control and Prevention (CDC) recommend the following steps to reduce the spread of CMV:
Beckham JD, Solbrig MV, Tyler KL. Viral encephalitis and meningitis. In: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, eds. Bradley's Neurology in Clinical Practice. 7th ed. Philadelphia, PA: Elsevier; 2016:chap 78.
Crumpacker CS. Cytomegalovirus (CMV). In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, Updated Edition. 8th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 140.
Huang FAS, Brady RC. Congenital and perinatal infections. In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Textbook of Pediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020:chap 131.BACK TO TOP
Review Date: 4/4/2019
Reviewed By: Liora C. Adler, MD, Pediatric Emergency Medicine, Joe DiMaggio Children’s Hospital, Hollywood, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
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