Renal cancer; Kidney cancer; Hypernephroma; Adenocarcinoma of renal cells; Cancer - kidney
Renal cell carcinoma is a type of kidney cancer that starts in the lining of very small tubes (tubules) in the kidney.
Renal cell carcinoma is the most common type of kidney cancer in adults. It occurs most often in men 60 to 70 years old.
The exact cause is unknown.
The following may increase your risk of kidney cancer:
Symptoms of this cancer may include any of the following:
The health care provider will perform a physical exam. This may reveal a mass or swelling of the abdomen.
Tests that may be ordered include:
The following tests may be done to see if the cancer has spread:
Surgery to remove all or part of the kidney (nephrectomy) is usually recommended. This may include removing the bladder, surrounding tissues, or lymph nodes. A cure is unlikely unless all of the cancer is removed with surgery. But even if some cancer is left behind, there may be a benefit from surgery.
Chemotherapy is generally not effective for treating kidney cancer in adults. Newer immune system medicines may help some people. Medicines that target the development of blood vessels that feed the tumor may be used to treat kidney cancer. Your provider can tell you more.
Radiation therapy is usually done when the cancer spreads to the bone or brain.
You can ease the stress of illness by joining a support group whose members share common experiences and problems.
Sometimes, both kidneys are involved. The cancer spreads easily, most often to the lungs and other organs. In about one fourth of people, the cancer has already spread (metastasized) at the time of diagnosis.
How well someone with kidney cancer does depends on how much the cancer has spread and how well treatment works. The survival rate is highest if the tumor is in the early stages and has not spread outside the kidney. If it has spread to the lymph nodes or to other organs, the survival rate is much lower.
Complications of kidney cancer include:
Contact your provider any time you see blood in the urine. Also contact if you have any other symptoms of this disorder.
Stop smoking. Follow your provider's recommendations in the treatment of kidney disorders, especially those that may require dialysis.
National Cancer Institute website. Renal cell cancer treatment (PDQ) -- health professional version. www.cancer.gov/types/kidney/hp/kidney-treatment-pdq. Updated April 1, 2022. Accessed June 24, 2022.
National Comprehensive Cancer Network website. NCCN clinical practice guidelines in oncology: kidney cancer. Version 2.2022. www.nccn.org/professionals/physician_gls/pdf/kidney.pdf . Updated September 8, 2021. Accessed June 24, 2022.
Weiss RH, Jaimes EA, Hu SL. Kidney cancer. In: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, eds. Brenner and Rector's The Kidney. 11th ed. Philadelphia, PA: Elsevier; 2020:chap 41.BACK TO TOP
Review Date: 1/25/2022
Reviewed By: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
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