Ovarian cancer

An in-depth report on the causes, diagnosis, treatment, and prevention of ovarian cancer.

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American College of Obstetricians and Gynecologists Committee on Gynecologic Practice. Committee Opinion No. 477: the role of the obstetrician-gynecologist in the early detection of epithelial ovarian cancer. Obstet Gynecol. 2011;117(3):742-746. PMID: 21343791 www.ncbi.nlm.nih.gov/pubmed/21343791.

Coleman RL, Liu J, Matsuo K, Thaker PH, Westin SN, Sood AK. Carcinoma of the ovaries and fallopian tubes. In: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6th ed. Philadelphia, PA: Elsevier; 2020:chap 86.

Coleman RL, Ramirez PT, Gershenson DM. Neoplastic diseases of the ovary: screening, benign and malignant epithelial and germ cell neoplasms, sex-cord stromal tumors. In: Lobo RA, Gershenson DM, Lentz GM, Valea FA, eds. Comprehensive Gynecology. 7th ed. Philadelphia, PA: Elsevier; 2017:chap 33.

Cortez AJ, Tudrej P, Kujawa KA, Lisowska KM. Advances in ovarian cancer therapy. Cancer Chemother Pharmacol. 2018;81(1):17-38. PMID: 29249039 www.ncbi.nlm.nih.gov/pubmed/29249039.

Doubeni CA, Doubeni AR, Myers AE. Diagnosis and management of ovarian cancer. Am Fam Physician. 2016;93(11):937-944. PMID: 27281838 www.ncbi.nlm.nih.gov/pubmed/27281838.

Finch AP, Lubinski J, Møller P, et al. Impact of oophorectomy on cancer incidence and mortality in women with a BRCA1 or BRCA2 mutation. J Clin Oncol. 2014;32(15):1547-1553. PMID: 24567435 www.ncbi.nlm.nih.gov/pubmed/24567435.

Henderson JT, Webber EM, Sawaya GF. Screening for ovarian cancer: Updated evidence report and systematic review for the US Preventive Services Task Force. JAMA. 2018;319(6):595-606. PMID: 29450530 www.ncbi.nlm.nih.gov/pubmed/29450530.

Lheureux S, Gourley C, Vergote I, Oza AM. Epithelial ovarian cancer. Lancet. 2019;393(10177):1240-1253. PMID: 30910306 www.ncbi.nlm.nih.gov/pubmed/30910306.

Loren AW, Mangu PB, Beck LN, et al. Fertility preservation for patients with cancer: American Society of Clinical Oncology clinical practice guideline update. J Clin Oncol. 2013;31(19):2500-2510. PMID: 23715580 www.ncbi.nlm.nih.gov/pubmed/23715580.

Mavaddat N, Peock S, Frost D, et al. Cancer risks for BRCA1 and BRCA2 mutation carriers: results from prospective analysis of EMBRACE. J Natl Cancer Inst. 2013;105(11):812-822. PMID: 23628597 www.ncbi.nlm.nih.gov/pubmed/23628597.

Moyer VA; U.S. Preventive Services Task Force. Risk assessment, genetic counseling, and genetic testing for BRCA-related cancer in women: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med. 2014;160(4):271-281. PMID: 24366376 www.ncbi.nlm.nih.gov/pubmed/24366376.

National Cancer Institute website. Ovarian, fallopian tube, and primary peritoneal cancer prevention (PDQ) - health professional version. www.cancer.gov/types/ovarian/hp/ovarian-prevention-pdq. Updated December 13, 2019. Accessed December 27, 2019.

National Comprehensive Cancer Network website. Genetic/Familial High-Risk Assessment: Breast and Ovarian.Version 3.2019. www.nccn.org/professionals/physician_gls/PDF/genetics_screening.pdf. Updated January 18, 2019. Accessed June 20, 2019.

National Comprehensive Cancer Network website. Ovarian cancer including fallopian tube cancer and primary peritoneal cancer.Version 1.2019. www.nccn.org/professionals/physician_gls/PDF/ovarian.pdf. Updated March 8, 2019. Accessed June 20, 2019.

Neff RT, Senter L, Salani R. BRCA mutation in ovarian cancer: testing, implications and treatment considerations. Ther Adv Med Oncol. 2017;9(8):519-531. PMID: 28794804 www.ncbi.nlm.nih.gov/pubmed/28794804.

Torre LA, Trabert B, DeSantis CE, et al. Ovarian cancer statistics, 2018. CA Cancer J Clin. 2018;68(4):284-296. PMID: 29809280 www.ncbi.nlm.nih.gov/pubmed/29809280.


Review Date: 8/26/2019  

Reviewed By: Howard Goodman, MD, Gynecologic Oncology, Florida Cancer Specialists & Research Institute, West Palm Beach, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

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