Crohn disease

An in-depth report on the causes, diagnosis, treatment, and prevention of Crohn disease.

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References

Adamina M, Bonovas S, Raine T, et al. ECCO Guidelines on therapeutics in Crohn's disease: surgical treatment. J Crohns Colitis. 2020;14(2):155-168. PMID: 31742338 pubmed.ncbi.nlm.nih.gov/31742338/.

Ananthakrishnan AN, Regueiro MD. Management of inflammatory bowel disease. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 11th ed. Philadelphia, PA: Elsevier; 2021:chap 116.

Bye WA, Nguyen TM, Parker CE, Jairath V, East JE. Strategies for detecting colon cancer in patients with inflammatory bowel disease. Cochrane Database Syst Rev. 2017;9:CD000279. PMID: 28922695 pubmed.ncbi.nlm.nih.gov/28922695/.

Chande N, Townsend CM, Parker CE, MacDonald JK. Azathioprine or 6-mercaptopurine for induction of remission in Crohn's disease. Cochrane Database Syst Rev. 2016;10:CD000545. PMID: 27783843 pubmed.ncbi.nlm.nih.gov/27783843/.

Cheifetz AS. Management of active Crohn disease. JAMA. 2013;309(20):2150-2158. PMID: 23695484 pubmed.ncbi.nlm.nih.gov/23695484/.

Cushing K, Higgins PDR. Management of Crohn disease: a review. JAMA. 2021;325(1):69-80. PMID: 33399844 pubmed.ncbi.nlm.nih.gov/33399844/.

Farraye FA, Odze RD, Eaden J, et al. AGA medical position statement on the diagnosis and management of colorectal neoplasia in inflammatory bowel disease. Gastroenterology. 2010;138(2):738-745. PMID: 20141808 pubmed.ncbi.nlm.nih.gov/20141808/.

Feuerstein JD, Ho EY, Shmidt E, et al; American Gastroenterological Association Institute Clinical Guidelines Committee. AGA Clinical Practice Guidelines on the medical management of moderate to severe luminal and perianal fistulizing Crohn's disease. Gastroenterology. 2021;160(7):2496-2508. PMID: 34051983 pubmed.ncbi.nlm.nih.gov/34051983/.

Kaplan GG, Ng SC. Epidemiology, pathogenesis, and diagnosis of inflammatory bowel diseases. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 11th ed. Philadelphia, PA: Elsevier; 2021:chap 115.

Lichtenstein GR. Inflammatory bowel disease. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 132.

Lim WC, Wang Y, MacDonald JK, Hanauer S. Aminosalicylates for induction of remission or response in Crohn's disease. Cochrane Database Syst Rev. 2016;7:CD008870. PMID: 27372735 pubmed.ncbi.nlm.nih.gov/27372735/.

Nguyen GC, Loftus EV Jr, Hirano I, et al; AGA Institute Clinical Guidelines Committee. American Gastroenterological Association Institute Guideline on the management of Crohn's disease after surgical resection. Gastroenterology. 2017;152(1):271-275. PMID: 27840074 pubmed.ncbi.nlm.nih.gov/27840074/.

Rezaie A, Kuenzig ME, Benchimol EI, et al. Budesonide for induction of remission in Crohn's disease. Cochrane Database Syst Rev. 2015;(6):CD000296. PMID: 26039678 pubmed.ncbi.nlm.nih.gov/26039678/.

Rosen MJ, Dhawan A, Saeed SA. Inflammatory bowel disease in children and adolescents. JAMA Pediatr. 2015;169(11):1053-1060. PMID: 26414706 pubmed.ncbi.nlm.nih.gov/26414706/.

Shouval DS, Rufo PA. The role of environmental factors in the pathogenesis of inflammatory bowel diseases: a review. JAMA Pediatr. 2017;171(10):999-1005. PMID: 28846760 pubmed.ncbi.nlm.nih.gov/28846760/.

Singh S, Proctor D, Scott FI, Falck-Ytter Y, Feuerstein JD. AGA technical review on the medical management of moderate to severe luminal and perianal fistulizing Crohn's disease. Gastroenterology. 2021;160(7):2512-2556.e9. PMID: 34051985 pubmed.ncbi.nlm.nih.gov/34051985/.

Strong S, Steele SR, Boutrous M, et al; Clinical Practice Guidelines Committee of the American Society of Colon and Rectal Surgeons. Clinical practice guideline for the surgical management of Crohn's disease. Dis Colon Rectum. 2015;58(11):1021-1036. PMID: 26445174 pubmed.ncbi.nlm.nih.gov/26445174/.

Terdiman JP, Gruss CB, Heidelbaugh JJ, Sultan S, Falck-Ytter YT; AGA Institute Clinical Practice and Quality Management Committee. American Gastroenterological Association Institute guideline on the use of thiopurines, methotrexate, and anti-TNF-a biologic drugs for the induction and maintenance of remission in inflammatory Crohn's disease. Gastroenterology. 2013;145(6):1459-1463. PMID: 24267474 pubmed.ncbi.nlm.nih.gov/24267474/.

Torres J, Mehandru S, Colombel JF, Peyrin-Biroulet L. Crohn's disease. Lancet. 2017;389(10080):1741-1755. PMID: 27914655 pubmed.ncbi.nlm.nih.gov/27914655/.

Torres J, Bonovas S, Doherty G, et al. ECCO Guidelines on therapeutics in Crohn's disease: medical treatment. J Crohns Colitis. 2020;14(1):4-22. PMID: 31711158 pubmed.ncbi.nlm.nih.gov/31711158/.

Veauthier B, Hornecker JR. Crohn's Disease: diagnosis and management. Am Fam Physician. 2018;98(11):661-669. PMID: 30485038 pubmed.ncbi.nlm.nih.gov/30485038/.

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Review Date: 6/6/2021  

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