Pronunciation:

TRAV-oh-prost

Brand Names:

• iDose TR
• Izba
• Travatan
• Travatan Z

Dosage Forms:

• Solution
• Implant

Classifications:

Therapeutic—

Antiglaucoma

Pharmacologic—

Prostaglandin

Uses of This Medicine:

Travoprost eye drops are used to treat increased pressure in the eye caused by open-angle glaucoma or hypertension of the eye. Both conditions are caused by high pressure in the eye which can lead to pain or vision changes. This medicine is a prostaglandin.

This medicine is available only with your doctor's prescription.

Before Using This Medicine:

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies—

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Children—

Because of travoprost's side effects, use in children younger than 16 years of age is not recommended.

Older adults—

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of travoprost eye drops in the elderly.

Breast-feeding—

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Other medicines—

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Other interactions—

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other medical problems—

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Eye infection (bacterial keratitis) or
• Eye lens problems or
• Macular edema (swelling in the back part of the eye) or
• Uveitis (eye inflammation)—Use with caution. May make these conditions worse.

Proper Use of This Medicine:

Your eye doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to.

Your doctor may order 2 or more eye drops to be used together. You should wait at least 5 minutes before putting another eye drop in the same eye.

Remove contact lenses before using this medicine. Wait at least 15 minutes after using this medicine before putting the contact lenses back in.

To use:

• The bottle is only partially full to provide proper drop control.
• First, wash your hands. Tilt your head back and, pressing your finger gently on the skin just beneath the lower eyelid, pull the lower eyelid away from the eye to make a space. Drop the medicine into this space. Let go of the eyelid and gently close the eyes. Do not blink. Keep the eyes closed for 1 to 2 minutes to allow the medicine to cover the eye.
• Remove any excess solution around the eye with a clean tissue, being careful not to touch the eye.
• Immediately after using the eye drops, wash your hands to remove any medicine that may be on them.
• To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). Also, keep the container tightly closed.

Dosing—

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For ophthalmic dosage form (eye drops):
  • For glaucoma or hypertension of the eye:
    • Adults and children 16 years of age and older—Use one drop in the affected eye once a day in the evening.
    • Children younger than 16 years of age—Use is not recommended.

Missed dose—

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage—

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using This Medicine:

Your eye doctor will want to examine your eyes at regular visits to make sure that this medicine is working properly and is not causing unwanted effects.

This medicine may cause the iris (colored part), eyelid, or eyelashes of your treated eye to turn brown. Your eyelashes may also become longer, thicker, and darker. Some of these changes may be permanent even if you stop using travoprost. Check with your doctor if you have any questions about this.

Check with your doctor right away if you have an eye injury, eye infection, or plan to have eye surgery.

Side Effects of This Medicine:

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Eye pain

itching eye

redness of the eye

redness, swelling, or itching of eyelid

Less common

Blurred or decreased vision

burning, dry, or itching eyes

eye color changes

redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Eye discomfort

feeling of having something in the eye

Less common

Acid or sour stomach (heartburn or indigestion)

blood in the urine

chest pain or tightness

dry eyes

eye discharge or excessive tearing

faintness or lightheadedness when getting up from a lying or sitting position

loss of bladder control

lower back pain

muscle pain or stiffness

pain, swelling, or redness in the joints

pain or burning while urinating

pelvic pain

slow or irregular heartbeat (less than 50 beats per minute)

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.