Vorasidenib (By mouth)
Vorasidenib (vor-a-SID-e-nib)
Treats brain tumor.
Brand Name(s):
Voranigo
There may be other brand names for this medicine.When This Medicine Should Not Be Used:
This medicine is not right for everyone. Do not use it if you had an allergic reaction to vorasidenib.How to Use This Medicine:
Tablet
- Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
- Swallow the tablet whole with water. Do not split, crush, or chew it.
- Take this medicine at the same time each day.
- Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
- Missed dose:
- If you miss a dose and it is less than 6 hours, take the missed dose as soon as possible, and then go back to your regular schedule. If you miss a dose and it is more than 6 hours, skip the missed dose and take your next dose at the regular time. Do not use extra medicine to make up for a missed dose.
- If you vomit after taking a dose of this medicine, do not take an additional dose. Take your next dose at your usual time.
- Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Do not remove or swallow the drying agent (desiccant canister) in your medicine bottle. The drying agent will protect your medicine from moisture.
Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Some food and medicines can affect how vorasidenib works. Tell your doctor if you are using birth control pills, ciprofloxacin, fluvoxamine, phenytoin, or rifampin.
Warnings While Using This Medicine:
- This medicine may cause birth defects if either partner is using it during conception or pregnancy. Tell your doctor right away if you or your partner becomes pregnant. If you can get pregnant, your doctor may do tests to make sure you are not pregnant before starting treatment. Birth control pills may not work as well to prevent pregnancy when used with this medicine. Female patients should use another form of birth control (including condoms or spermicide) during treatment and for 3 months after your last dose. Male patients with female partners should use an effective form of birth control during treatment and for at least 3 months after the last dose.
- Do not breastfeed during treatment with this medicine and for 2 months after the last dose.
- Tell your doctor if you have kidney disease, liver disease, or if you smoke tobacco.
- This medicine may cause liver problems.
- Medicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.
- This medicine could cause infertility. Talk with your doctor before using this medicine if you plan to have children.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
- Keep all medicine out of the reach of children. Never share your medicine with anyone.
Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
- Fever, chills, cough, sore throat, body aches
- Seizures
If you notice these less serious side effects, talk with your doctor:
- Constipation, diarrhea
- Headache
- Muscle or joint pain
- Tiredness
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
Last Updated: 2/4/2025