Epcoritamab-bysp (By injection)

Epcoritamab-bysp (ep-koe-RIT-a-mab - bysp)

Treats lymphoma, including diffuse large B-cell lymphoma and high grade B-cell lymphoma.

Brand Name(s):

Epkinly

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right fro everyone. You should not receive it if you had an allergic reaction to epcoritamab-bysp.

How to Use This Medicine:

Injectable

• Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin. This medicine is usually given in the stomach or thigh.
• You will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.
• You doctor may also give you other medicines (including allergy medicine, steroid, fever medicine) 30 to 120 minutes before starting treatment with this medicine.
• This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine:

• It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. If you are a woman who can get pregnant, your doctor may do tests to make sure you are not pregnant before starting treatment. Use an effective form of birth control to keep from getting pregnant during treatment and for 4 months after the last dose.
• Do not breastfeed during treatment and for 4 months after the last dose.
• Tell your doctor if you have an infection.
• This medicine may cause the following problems:
  • Cytokine release syndrome, which may be life-threatening
  • Nervous system problems, including immune effector cell-associated neurotoxicity syndrome (ICANS)
  • Serious infections
• This medicine may cause dizziness, confusion, or tremors. Do not drive or do anything else that could be dangerous after receiving this medicine until you know how this medicine affects you.
• This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.
• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Chest pain, trouble breathing, fast, slow, or uneven heartbeat
• Fever, chills, cough, sore throat, body aches
• Muscle or bone pain
• Unusual bleeding, bruising, or weakness

If you notice these less serious side effects, talk with your doctor:

• Diarrhea, nausea, stomach pain
• Pain, itching, burning, swelling, or a lump under your skin where the shot was given

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 4/23/2024