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Pafolacianine (By injection)

Pafolacianine (paf-oh-la-SYE-a-neen)

Helps find and remove cancer lesions in the ovary during surgery.

Brand Name(s):

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. You should not receive it if you had an allergic reaction to pafolacianine.

How to Use This Medicine:

Injectable

  • Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. It must be given slowly, so the needle will have to remain in place for at least 60 minutes. You will receive this medicine 1 to 9 hours before surgery.
  • A nurse or other health provider will give you this medicine.
  • You may also receive other medicines (including allergy medicine, medicine to prevent nausea) before you receive this medicine.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Do not take folate, folic acid, or supplements containing folate 48 hours before receiving this medicine.

Warnings While Using This Medicine:

  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. If you are a woman who can get pregnant, your doctor may give you a pregnancy test before you start using this medicine to make sure you are not pregnant.
  • Tell your doctor if you are breastfeeding.
  • This medicine may cause infusion-related reactions.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Chest discomfort
  • Nausea, vomiting, stomach pain or upset
  • Pain, itching, burning, swelling, or a lump under your skin where the needle is placed
  • Warmth or redness in your face, neck, arms, or upper chest

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 12/4/2023

 

 
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