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Antihemophilic factor (Recombinant), Glycopegylated-exei (By injection)

Antihemophilic Factor (Recombinant), Glycopegylated-exei (an-tye-hee-moe-FIL-ik FAK-tor (re-KOM-bin-ant), glye-koe-PEG-il-ay-ted-exei)

Treats and controls bleeding in patients with hemophilia A, and reduces the number of bleeding episodes when used regularly. Also used to prevent bleeding during surgery.

Brand Name(s):

Esperoct

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. Do not use it if you had an allergic reaction to antihemophilic factor (recombinant), glycopegylated-exei or hamster proteins.

How to Use This Medicine:

Injectable

  • Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
  • A nurse or other health provider will give you this medicine.
  • You may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.
  • Swirl the vial gently to dissolve the powder. Do not shake. Do not use the mixed liquid if it is cloudy, discolored, or has particles in it.
  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
  • Missed dose: Ask your doctor or pharmacist for instructions if you need to use this medicine on a schedule.
  • You may store the unopened vial in the refrigerator for up to 30 months. Do not freeze. You may also store it at room temperature for up to 12 months. Do not place it back in the refrigerator once stored at room temperature. You may store the mixed liquid in the refrigerator for not more than 24 hours or at room temperature for not more than 4 hours. Throw away any unused medicine after 4 hours if kept at room temperature or after 24 hours if refrigerated.
  • Throw away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine:

  • Tell your doctor if you are pregnant or breastfeeding.
  • Tell your doctor if this medicine does not prevent or stop bleeding as expected.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Unexplained bleeding or bruising

If you notice these less serious side effects, talk with your doctor:

  • Pain, itching, burning, redness, swelling, or a lump under your skin where the needle is placed

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 12/4/2023

 

 
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