Trastuzumab-dttb (By injection)

Trastuzumab-dttb (tras-TOOZ-oo-mab - dttb)

Treats cancer, including breast, esophagus, and stomach cancer.

Brand Name(s):

Ontruzant

When This Medicine Should Not Be Used:

How to Use This Medicine:

Injectable

• Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. This medicine must be given slowly, so the needle will have to stay in place for at least 30 to 90 minutes.
• You will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.
• Missed dose: This medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Avoid using other cancer medicines (including anthracyclines) for up to 7 months after stopping treatment with trastuzumab-dttb.

Warnings While Using This Medicine:

• It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. Use an effective form of birth control during treatment with this medicine and for 7 months after the last dose.
• Tell your doctor if you are breastfeeding, or if you have heart disease, lung disease, or breathing problems.
• This medicine may cause the following problems:
  • Heart problems, including heart rhythm problems, heart failure, or high blood pressure
  • Infusion reactions
  • Lung problems
• Medicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.
• This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.
• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Fainting, dizziness, lightheadedness
• Fast, pounding, or uneven heartbeat
• Fever, chills, cough, sore throat, body aches
• Rapid weight gain, swelling in your hands, ankles, or feet
• Trouble breathing, cold sweat, bluish-colored skin, chest pain or tightness
• Unusual bleeding, bruising, or weakness

If you notice these less serious side effects, talk with your doctor:

• Decreased weight, change in taste
• Headache
• Muscle pain or weakness
• Nausea, vomiting, diarrhea
• Numbness, tingling, or burning pain in your hands, arms, legs, or feet
• Pain, itching, burning, swelling, or a lump under your skin where the needle is placed

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 4/23/2024