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Ertugliflozin (By mouth)

Ertugliflozin (er-too-gli-FLOE-zin)

Treats type 2 diabetes.

Brand Name(s):

Steglatro

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. Do not use it if you had an allergic reaction to ertugliflozin.

How to Use This Medicine:

Tablet

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
  • Take this medicine in the morning.
  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Some medicines can affect how ertugliflozin works. Tell your doctor if you are using lithium, a diuretic (water pill), insulin, or other diabetes medicine.

Warnings While Using This Medicine:

  • Tell your doctor if you are pregnant. Do not use this medicine during the second and third part of your pregnancy, unless your doctor tells you to.
  • Tell your doctor if you have kidney disease, liver disease, low blood pressure, blood vessel problems, nerve problems, or a history of leg surgery, or foot ulcers or urinary or genital yeast infections. Tell your doctor if you are on a low-salt diet, if you drink alcohol, or if you are having surgery or other procedures that require fasting.
  • Do not breastfeed during treatment with this medicine.
  • This medicine may cause the following problems:
    • Low blood pressure
    • Diabetic ketoacidosis (high ketones and acid in the blood), which can be life-threatening
    • Kidney problems
    • Increased risk of genital yeast or urinary tract infections
    • Increased risk for lower leg or toe amputation (removal)
    • Low blood sugar, when used with other diabetes medicine
    • Fournier's gangrene (skin or tissue damage of the area between the anus and genitals)
  • This medicine may cause some patients to become dehydrated. Drink plenty of water every day, during exercise, or in hot weather.
  • Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.
  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Change in how much or how often you urinate, bloody urine, difficult or painful urination, lower back or side pain, chills
  • Fast breathing, nausea, vomiting, severe weakness
  • Lightheadedness, dizziness, or fainting
  • Pain, tenderness, redness, or swelling of the area between the anus and genitals, fever, unusual tiredness or weakness
  • Pain, tenderness, sores or ulcers, or infections on the leg or foot
  • Shaking, trembling, sweating, fast or pounding heartbeat, faintness, hunger, confusion

If you notice these less serious side effects, talk with your doctor:

  • White or yellow vaginal or penile discharge, vaginal or penile itching or odor

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 12/4/2023

 

 
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