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Panitumumab (By injection)

Panitumumab (pan-i-TOOM-ue-mab)

Treats cancer of the colon or rectum.

Brand Name(s):

Vectibix

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. You should not receive it if you had an allergic reaction to panitumumab, or if you are pregnant.

How to Use This Medicine:

Injectable

  • Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. This medicine needs to be given slowly, so the needle will have to remain in place for at least an hour.
  • You will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.
  • Missed dose: This medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine:

  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. Use an effective form of birth control during treatment with this medicine and for at least 2 months after the last dose.
  • Do not breastfeed during treatment with this medicine and for at least 2 months after the last dose.
  • Tell your doctor if you have kidney disease, or a history of lung or breathing problems.
  • Medicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.
  • This medicine may cause the following problems:
    • Severe skin rash or infections, which could be life-threatening
    • Infusion reactions
    • Kidney problems
    • Lung problems, including pulmonary fibrosis or interstitial lung disease
    • Eye or vision problems
  • Avoid overexposing your skin to sunlight. Always use sunscreen or sun blocking lotions and wear protective clothing and hats while you are receiving this medicine and for 2 months after the last dose.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blistering, peeling, red skin rash
  • Blurred vision or vision changes, eye redness or pain, watery eyes
  • Change in how much or how often you urinate, rapid weight gain, swelling in your hands, ankles, or feet
  • Chest pain, trouble breathing, cough, cold sweat, or bluish-colored skin
  • Dry, itchy, or cracking skin, acne, fingernail changes or swelling around your nails
  • Dry mouth, increased thirst, muscle cramps, uneven heartbeat
  • Fever, chills, chest tightness, faintness
  • Redness, swelling, peeling, or tenderness of the hands or feet
  • Severe diarrhea, nausea, or vomiting
  • Unusual tiredness or weakness, muscle cramps, confusion

If you notice these less serious side effects, talk with your doctor:

  • Mild diarrhea, nausea, or vomiting

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 12/4/2023

 

 
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