Tenecteplase (Into a vein)
Tenecteplase (ten-EK-te-plase)
Reduces the risk of death caused by heart attack.
Brand Name(s):
TNKase
There may be other brand names for this medicine.When This Medicine Should Not Be Used:
This medicine is not right for everyone. You should not receive this medicine if you had an allergic reaction to tenecteplase, or if you have active bleeding, uncontrolled high blood pressure, surgery or trauma within 2 months, brain cancer, blood vessel disease, or known bleeding.How to Use This Medicine:
Injectable
- Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. The medicine must be given slowly, so the needle will have to remain in place for at least 5 seconds.
- A nurse or other health provider will give you this medicine.
Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
Warnings While Using This Medicine:
- Tell your doctor if you are pregnant or breastfeeding, or if you have bleeding problems, blood clotting problems, heart failure, or heart rhythm problems.
- This medicine may cause the following problems:
- Bleeding problems
- Blood clotting problems, including thromboembolism
- Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
- Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blood in the urine or stools
- Chest pain, trouble breathing, coughing or vomiting blood
- Fever
- Lightheadedness or fainting
- Numbness or weakness in your arm or leg, or on one side of your body
- Numbness, tingling, pain, or darkening of the skin of your toes
- Sudden or severe headache, problems with vision, speech, or walking
- Unusual bruising, bleeding, swelling, or pain anywhere in your body
If you notice these less serious side effects, talk with your doctor:
- Nausea or vomiting
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
Last Updated: 12/4/2023
