Sulfacetamide (On the skin)

Sulfacetamide (sul-fa-SET-a-mide)

Treats dandruff and skin infections caused by certain types of bacteria.

Brand Name(s):

Klaron, Ovace Plus Creme, Ovace Plus Foam, Ovace Plus Lotion, Ovace Plus Shampoo, Ovace Plus Wash, Ovace Plus Wash Clean Gel, Ovace Wash

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to sulfacetamide or to other sulfa medicines such as trimethoprim/sulfamethoxazole, Bactrim®, Cotrim®, or Septra®. You should not use this medicine if you have had an allergic reaction to silver or sulfites. Do not use this medicine on a child under 12 years old without a doctor's approval.

How to Use This Medicine:

Cream, Foam, Liquid, Gel/Jelly, Lotion, Pad, Soap

  • Your doctor will tell you how much medicine to use. Do not use more than directed.
  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
  • Use this medicine only on your skin. Rinse it off right away if it gets on a cut or scrape. Do not get the medicine in your eyes, nose, or mouth.
  • To use on your head: Wash your hair with a mild shampoo, and clean your scalp well with water. Brush your hair for 2 to 3 minutes after you apply this medicine.
  • Wash your hands with soap and water before and after you use this medicine.
  • Apply a thin layer of the medicine to the affected area. Rub it in gently.

If a dose is missed:

  • Apply a dose as soon as you can. If it is almost time for your next dose, wait until then and apply a regular dose. Do not apply extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine:

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • Ask your pharmacist or doctor how to dispose of the medicine container and any leftover or expired medicine.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are using other sulfonamides (sulfa drug) such as trimethoprim/sulfamethoxazole, Bactrim®, Cotrim®, or Septra®.
  • Do not put cosmetics or skin care products on the treated skin.

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breast feeding, or if you have a fungus infection. If you have any open wounds on the area you are going to treat, ask your doctor before using this medicine.
  • Call your doctor if your symptoms do not improve or if they get worse.
  • Do not use this medicine to treat a skin problem your doctor has not examined.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blistering, peeling, red skin rash.
  • Fever, or soreness in your mouth.
  • Joint pains.
  • Nausea or vomiting.

If you notice these less serious side effects, talk with your doctor:

  • Rash, irritation, itching, or burning.
  • Swelling in hands, ankles, or feet.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 11/6/2020

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites.

All rights reserved

A.D.A.M. content is best viewed in IE9 or above, Firefox and chrome browser.