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General anesthesia (By injection)

This medicine causes a person to relax or sleep (be unconscious) before and during a surgery. Also given to people in an intensive care unit (ICU).

Brand Name(s):

Amidate, Amidate Novaplus

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not receive this medicine if you have had an allergic reaction to any type of general anesthesia. You should not receive this medicine if you are breast feeding.

How to Use This Medicine:

Injectable

  • Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
  • You will receive this medicine in a hospital or surgery center. A nurse or other health provider will give you this medicine.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Tell your doctor if you use anything else that makes you sleepy. Some examples are allergy medicine, narcotic pain medicine, and alcohol.

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breast feeding. Tell your doctor if you have diabetes, kidney disease, pancreas problems, or high cholesterol. Make sure your doctor knows if you have ever had a head injury, stroke, or seizures, including epilepsy.
  • This medicine may make you dizzy or drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Lightheadedness or fainting (after you awake from surgery).
  • Muscle stiffness.
  • Seizures.
  • Slow or uneven heartbeat.

If you notice these less serious side effects, talk with your doctor:

  • Blurred vision.
  • Cough, sore throat.
  • Headache, mood changes, unusual dreams.
  • Mild nausea or vomiting.
  • Mild skin rash.
  • Muscle pain, tightness, or weakness.
  • Pain, swelling, or skin changes where the needle is placed.
  • Shivering, shaking, or trembling.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 12/4/2023

 

 
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