Fenofibrate (By mouth)

Fenofibrate (fen-oh-FYE-brate)

Lowers high cholesterol and triglyceride levels.

Brand Name(s):

Antara, Fenoglide, Lipofen, Tricor, Triglide

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. Do not use it if you had an allergic reaction to fenofibrate or fenofibric acid, or you are breastfeeding. Do not use it if you receive kidney dialysis or have active liver disease or gallbladder disease.

How to Use This Medicine:

Capsule, Tablet

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
  • Take Fenoglide®, Lipofen®, or Tricor® with a meal. Antara® and Triglide® can be taken with or without a meal.
  • Swallow Antara® capsules, Triglide® tablets, or Tricor® tablets whole. Do not open, crush, break, chew, or dissolve them.
  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Some medicines can affect how fenofibrate works. Tell your doctor if you are using any of the following:
    • Colchicine
    • Cyclosporine
    • Tacrolimus
    • A blood thinner (such as warfarin)
    • A statin medicine to lower cholesterol, such as atorvastatin, pravastatin, or simvastatin
  • If you are also using cholestyramine, colesevelam, or colestipol, you must take fenofibrate at least 1 hour before or 4 to 6 hours after you take these medicines.

Warnings While Using This Medicine:

  • Tell your doctor if you are pregnant, or if you have kidney disease, blood clotting problems, diabetes, heart disease, or thyroid problems.
  • This medicine may cause the following problems:
    • Myopathy or rhabdomyolysis (serious muscle problems)
    • Pancreatitis
    • Increased risk of gallstones
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blistering, peeling, red skin rash
  • Chest pain, trouble breathing, coughing up blood
  • Dark urine or pale stools, yellow skin or eyes
  • Muscle pain, tenderness, or weakness
  • Sudden and severe stomach pain, nausea, vomiting, fever, or loss of appetite
  • Unusual bleeding, bruising, or weakness

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 11/6/2020

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