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Momelotinib (By mouth)

Momelotinib (moe-me-LOE-ti-nib)

There may be other brand names for this medicine.

This medicine is not right for everyone. Do not use it if you had an allergic reaction to momelotinib.

Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
Swallow the tablet whole. Do not cut, crush, or chew it.
Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
Missed dose: If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not take extra medicine to make up for a missed dose.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Some medicines can affect how momelotinib works. Tell your doctor if you are using rifampin or rosuvastatin.

It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. Use an effective form of birth control during treatment and for 1 week after the last dose.
Do not breastfeed during treatment and for 1 week after the last dose.
Tell your doctor if you have kidney disease, liver disease (including hepatitis B), heart or blood vessel disease, any type of infection, or a history of blood clots, heart attack, stroke, or skin cancer. Tell your doctor if you are a current or past smoker.
This medicine may cause the following problems:
- Increased risk of serious infections
- Liver problems
- Increased risk of serious heart or blood vessel disease, including heart attack or stroke
- Increased risk of blood clots, including deep vein thrombosis, pulmonary embolism, arterial thrombosis
- Increased risk of cancer, including lymphoma, skin cancer
This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.
Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Keep all medicine out of the reach of children. Never share your medicine with anyone.

Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Chest pain that may spread to your arms, jaw, back, or neck, trouble breathing, nausea, unusual sweating, fainting
Coughing up blood, numbness or weakness in your arm or leg, or on one side of your body, pain in your lower leg
Dark urine or pale stools, vomiting, loss of appetite, stomach pain, yellow skin or eyes
Fever, chills, cough, sore throat, body aches
Rapid weight gain, swelling in your hands, ankles, or feet
Sores, reddish patch or irritated area, shiny bump, or pink growth on the skin
Sudden or severe headache, problems with vision, speech, or walking
Unusual bleeding, bruising, or weakness

Last Updated: 4/23/2024