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Belumosudil (By mouth)

Belumosudil (bel-ue-MOE-soo-dil)

There may be other brand names for this medicine.

This medicine is not right for everyone. Do not use it if you had an allergic reaction to belumosudil, or if you are pregnant.

Take your medicine as directed. Your dose may need to be changed several times to find what works best for you. Take this medicine at the same time each day.
It is best to take this medicine with food or milk.
Swallow the tablet whole with a glass of water. Do not cut, crush, or chew it.
Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose. Take the missed dose only if it is the same day as the scheduled dose.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Some medicines can affect how belumosudil works. Tell your doctor if you are using efavirenz, midazolam, omeprazole, rabeprazole, or rifampin.

It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. If you are a woman who can get pregnant, your doctor may do tests to make sure you are not pregnant before starting treatment. Use an effective form of birth control during treatment and for at least 1 week after the last dose. Male patients with female partners should use an effective form of birth control during treatment and for at least 1 week after the last dose.
Do not breastfeed during treatment and for at least 1 week after the last dose.
Tell your doctor if you have kidney disease or liver disease.
This medicine could cause infertility. Talk with your doctor before using this medicine if you plan to have children.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Keep all medicine out of the reach of children. Never share your medicine with anyone.

Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Blurred vision, headache, slow or fast heartbeat, lightheadedness, dizziness
Chest pain, trouble breathing
Fever, chills, cough, runny or stuffy nose, sore throat, body aches
Muscle or bone pain
Rapid weight gain, swelling in your hands, ankles, or feet
Unusual bleeding, bruising, or weakness

Last Updated: 12/4/2023