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Voxelotor (By mouth)

Voxelotor (vox-EL-oh-tor)

There may be other brand names for this medicine.

This medicine is not right for everyone. Do not use it if you had an allergic reaction to voxelotor.

Your doctor will tell you how much medicine to use. Do not use more than directed.
Swallow the regular tablet whole. Do not crush, break, or chew it.
Tablet for suspension:
- Do not swallow whole, cut, crush, or chew the tablets.
- Mix the tablet in a room temperature clear liquid (including drinking water, apple juice, clear electrolyte drinks, clear flavored drinks, clear soda, or clear sports drinks) before swallowing.
- Swirl the oral liquid until the tablets break apart in the drink. The tablet will not completely dissolve. You will still see small tablet clumps in the mixture. Wait for 1 to 5 minutes, then swirl the mixture again and drink until no tablet residue is left in the cup.
Your doctor may want you to take hydroxyurea while taking this medicine.
Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
Missed dose: If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Do not use this medicine together with St John's wort.
Some medicines can affect how voxelotor works. Tell your doctor if you are using efavirenz, fluconazole, itraconazole, ketoconazole, midazolam, or rifampin.

Tell your doctor if you are pregnant or if you have liver disease. Tell your doctor if you are receiving blood transfusions.
Do not breastfeed during treatment and for at least 2 weeks after the last dose.
This medicine may cause serious skin reactions, including drug reaction with eosinophilia and systemic symptoms (DRESS).
Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Keep all medicine out of the reach of children. Never share your medicine with anyone.

Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Chest pain, trouble breathing
Fever, chills, cough sore throat, body aches
Swelling of the face, eyes, lips, or tongue
Unusual bleeding or bruising

Last Updated: 4/23/2024