Defibrotide (By injection)
Treats hepatic veno-occlusive disease after stem cell transplantation.
DefitelioThere may be other brand names for this medicine.
When This Medicine Should Not Be Used:This medicine is not right for everyone. You should not receive it if you had an allergic reaction to defibrotide.
How to Use This Medicine:
- Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
- A nurse or other health provider will give you this medicine.
Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Do not use this medicine if you are also using alteplase or heparin.
Warnings While Using This Medicine:
- Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease or bleeding problems.
- This medicine may increase your risk of bleeding.
- Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:
- Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
- Blood in urine or stools
- Chest pain, trouble breathing, coughing up blood
- Confusion, headache, problems with vision or speaking
- Lightheadedness, dizziness, fainting
- Unusual bleeding, bruising, or weakness
If you notice these less serious side effects, talk with your doctor:
- Nausea, vomiting, diarrhea
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
Last Updated: 6/18/2019