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Difluprednate (Into the eye)

Difluprednate (dye-floo-PRED-nate)

Treats eye irritation and inflammation. This medicine is a corticosteroid.

Brand Name(s):

Durezol

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. Do not use it if you had an allergic reaction to difluprednate.

How to Use This Medicine:

Liquid, Drop

  • Use this medicine as directed.
  • Remove contact lenses before you put the drops in your eyes. Wait at least 10 minutes after you use this medicine before you put your contact lenses back in.
  • Wash your hands with soap and water before and after using this medicine.
  • Lie down or tilt your head back. With your index finger, pull down the lower lid of your eye to form a pocket.
  • To use the eye drops: Hold the dropper close to your eye with the other hand. Drop the correct number of drops into the pocket made between your lower lid and eyeball. Gently close your eyes. Place your index finger over the inner corner of your eye for 1 minute. Do not rinse or wipe the dropper or allow it to touch anything, including your eye. Put the cap on the bottle right away. Keep the bottle upright when you are not using it.
  • Do not touch the eye dropper tip to any surface. This will help keep the medicine free of germs.
  • If you are using this medicine after eye surgery, use a separate bottle for each eye.
  • Missed dose: Apply a dose as soon as you can. If it is almost time for your next dose, wait until then and apply a regular dose. Do not apply extra medicine to make up for a missed dose.
  • Store the eye drop bottle in the protective carton at room temperature, away from heat, moisture, and direct light. Do not freeze.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine:

  • Tell your doctor if you are pregnant or breastfeeding, or if you have glaucoma, cataracts, or an eye infection. Tell your doctor if you had recent eye surgery.
  • This medicine may cause the following problems:
    • Increased pressure in your eye, which can damage the optic nerve
    • Posterior subcapsular cataracts (a rare type of cataract)
    • New or worsening eye infections
    • Slow or delayed healing after cataract surgery
  • If you hurt your eye, develop an eye infection, or need to have eye surgery, talk with your doctor right away. You may need to change your medicine or stop using it.
  • Call your doctor if your symptoms do not improve or if they get worse.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blurred vision, changes in vision
  • Eye pain
  • Increased discharge, redness, or irritation in your eye

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 12/4/2023

 

 
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