Enalaprilat (By injection)

Enalaprilat (en-AL-a-pril-at)

Treats high blood pressure. This medicine is an ACE inhibitor.

Brand Name(s):

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. Do not use it if you had an allergic reaction to enalaprilat or another ACE inhibitor, if you have hereditary angioedema, or if you are pregnant.

How to Use This Medicine:

Injectable

• Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
• A nurse or other health provider will give you this medicine.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Some medicines can affect how enalaprilat works. Tell your doctor if you are also using any of the following:
  • Lithium
  • A diuretic (water pill)
  • An NSAID pain or arthritis medicine such as aspirin, diclofenac, ibuprofen, or naproxen
  • Supplements or salt substitutes that contain potassium

Warnings While Using This Medicine:

• It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
• Tell your doctor if you are breastfeeding, if you have diabetes, heart disease, heart failure, kidney disease, a collagen vascular disease such as lupus or arthritis, or if you are on dialysis.
• This medicine may cause the following problems:
  • Liver problems
  • Kidney problems
  • Hyperkalemia (too much potassium in the blood)
• This medicine could lower your blood pressure too much, especially when you first use it or if you are dehydrated. Stand or sit up slowly if you are dizzy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
• Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.
• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Blistering, peeling, red skin rash
• Chest pain, fast or slow heartbeat
• Confusion, weakness, uneven heartbeat, trouble breathing, numbness in your hands, feet, or lips
• Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
• Decrease in how much or how often you urinate
• Fever, chills, sore throat, body aches
• Lightheadedness, dizziness, or fainting
• Unusual bleeding or bruising

If you notice these less serious side effects, talk with your doctor:

• Dry cough

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 12/4/2023