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Dexrazoxane (By injection)

Dexrazoxane (dex-ray-ZOX-ane)

There may be other brand names for this medicine.

This medicine is not right for everyone. You should not receive it if you are pregnant.

Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. It must be given slowly, so the needle will have to stay in place for 1 to 2 hours. If you are also taking doxorubicin: You will receive this medicine over 15 minutes before your doxorubicin treatment.
If you are using an ice pack or any other cooling procedure at the affected area, you may have to remove it at least 15 minutes before receiving this medicine.
You will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.
Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
Missed dose: This medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

Some medicines may affect how dexrazoxane works. Tell your doctor if you are also using other cancer treatments or topical dimethylsulfoxide (DMSO).

This medicine may cause birth defects if either partner is using it during conception or pregnancy. Tell your doctor right away if you or your partner becomes pregnant. Use an effective form of birth control during treatment with this medicine and for at least 6 months after the last dose. Male patients with female partners should use an effective form of birth control during treatment and for 3 months after the last dose.
Do not breastfeed during treatment with this medicine and for 2 weeks after your last dose.
Tell your doctor if you have liver disease, kidney disease, or a blood disorder.
If you are also taking doxorubicin: This medicine may not protect your heart completely. It is important to tell your doctor if you have any symptoms of heart problems, including trouble breathing, chest pain, lightheadedness, dizziness, or a fast or uneven heartbeat.
This medicine can increase your risk for certain cancers, including leukemia. Talk to your doctor if you have questions or concerns.
Talk with your doctor before receiving this medicine if you plan to have children. Some men who use this medicine have become infertile (unable to have children).
This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Fever, chills, cough, sore throat, body aches
Unusual bleeding, bruising, or weakness

Last Updated: 12/4/2023