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Narcotic-antitussive/antihistamine (By mouth)

Treats cough and runny nose caused by flu, allergies, or the common cold. This medicine is a combination that contains a narcotic cough suppressant.

Brand Name(s):

BroveX CB, BroveX CBX, Tuzistra XR

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to any cold or cough medicine, codeine, hydrocodone, chlorpheniramine, or any narcotic pain medicine such as Darvocet®, Percocet®, Demerol®, or Roxicodone®. This medicine should not be used in children under 6 years of age.

How to Use This Medicine:

Liquid, Tablet

  • Your doctor will tell you how much medicine to use. Do not use more than directed.
  • Shake the oral liquid well just before each use.
  • Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup. Do not dilute or mix the liquid with other fluids or medicine.
  • Drink plenty of liquids to help avoid constipation.

If a dose is missed:

  • Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine:

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Do not freeze.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using aspirin or an MAO Inhibitor (such as isocarboxacid, phenelzine, selegiline, tranylcypromine, Eldepryl®, Marplan®, Nardil®, or Parnate®).
  • Tell your doctor if you use anything else that makes you sleepy. Some examples are allergy medicine, narcotic pain medicine, and alcohol.
  • Do not drink alcohol while you are using this medicine.

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have Addison's disease, asthma or other breathing problems, gallbladder disease, glaucoma, kidney disease, liver disease, enlarged prostate or problems with urination, stomach or intestinal problems, thyroid disorder, or if you will be having any surgery. Tell your doctor if you have a history of stroke, seizures, head injury, mental illness, alcohol abuse, or drug abuse.
  • This medicine can be habit-forming. Do not use more than your prescribed dose. Call your doctor if you think your medicine is not working. Symptoms of an overdose include: extreme dizziness or weakness, shortness of breath, slow heartbeat, seizures, and cold, clammy skin.
  • Do not give this medicine to your child unless your doctor tells you to.
  • This medicine may make you dizzy or drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.
  • Call your doctor if your symptoms do not improve after using this medicine for a few days. Call your doctor if you also have a high fever or sore throat.
  • This medicine may cause constipation, especially with long-term use. Ask your doctor if you should use a laxative to prevent and treat constipation.
  • When a mother is breastfeeding and takes codeine, there is a very small chance that this medicine could cause serious side effects in the baby. This is because codeine works differently in a few women, so their breastmilk contains too much medicine. If you take codeine, be alert for these signs of overdose in your nursing baby: sleeping more than usual, trouble breastfeeding, trouble breathing, or being limp and weak. Call the baby's doctor right away if you think there is a problem. If you cannot talk to the doctor, take the baby to the emergency room or call 911.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blistering, peeling, or red skin rash.
  • Chest tightness, shortness of breath or shallow breathing, cold sweat, or bluish-colored skin.
  • Decrease in how much or how often you urinate.
  • Lightheadedness or fainting.
  • Severe confusion, weakness, or drowsiness.
  • Unusually slow heartbeat.

If you notice these less serious side effects, talk with your doctor:

  • Blurred vision.
  • Feelings of extreme happiness or sadness.
  • Mild skin rash or itching.
  • Muscle weakness.
  • Nausea, vomiting, constipation, or dry mouth.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 12/4/2023

 

 
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