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Alpha-1 proteinase inhibitor (By injection)

Alpha-1 Proteinase Inhibitor Human (AL-fa 1 PRO-teen-aze in-HIB-i-ter HUE-man)

Treats emphysema.

Brand Name(s):

Aralast NP, Glassia, Prolastin-C, Zemaira

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. You should not receive it if you had an allergic reaction to alpha-1 proteinase inhibitor.

How to Use This Medicine:

Injectable

  • Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
  • This medicine is usually given once a week on a regular schedule.
  • A nurse or other health provider will give you this medicine.
  • You may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.
  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
  • Record and keep a treatment infusion log. This includes information, including lot number, time, date, and any reactions.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Warnings While Using This Medicine:

  • Tell your doctor if you are pregnant or breastfeeding.
  • This medicine is made from donated human blood. All donated blood is tested for certain viruses. Although your risk for getting a virus from the medicine is very low, talk with your doctor if you have concerns. Your doctor may give you a hepatitis B vaccine before you receive this medicine.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Change in how much or how often you urinate, painful or difficult urination
  • Chest tightness or discomfort
  • Lightheadedness, dizziness, or fainting
  • Worsening of breathing problems

If you notice these less serious side effects, talk with your doctor:

  • Muscle or bone pain or discomfort
  • Pain, itching, burning, swelling, or a lump under your skin where the needle is placed
  • Warmth or redness in your face, neck, arms, or upper chest

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 12/4/2023

 

 
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