Keratoacanthomas are rapidly growing, red (erythematous), dome shaped bumps (papules/nodules) with central craters. Occasionally, these will disappear spontaneously (involute). Often, they are treated to avoid further involvement or destruction of underlying tissue. They are of concern because of the similarity to squamous cell cancer.
Review Date: 8/14/2021
Reviewed By: Elika Hoss, MD, Senior Associate Consultant, Mayo Clinic, Scottsdale, AZ. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. Editorial update 04/14/2022.