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Nikolsky sign

Nikolsky sign

Nikolsky sign

Nikolsky sign is a skin finding caused by a staphylococcal infection in which the superficial layers of skin slip free from the lower layers with a slight rubbing pressure. Large areas of the skin will blister and peel away leaving wet, red and painful areas.

 
Review Date: 2/18/2022

Reviewed By

Ramin Fathi, MD, FAAD, Director, Phoenix Surgical Dermatology Group, Phoenix, AZ. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

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