BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuCeruloplasmin blood testCP - serum; Copper - ceruloplasminThe ceruloplasmin test measures the level of the copper-containing protein ceruloplasmin in the blood. How the Test is Performed A blood sample is needed. Blood sampleVenipuncture is the collection of blood from a vein. It is most often done for laboratory testing.ImageRead Article Now Book Mark Article How to Prepare for the Test No special preparation is needed. How the Test will Feel When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging. Afterward, there may be some throbbing or a slight bruise. This soon goes away. Why the Test is Performed Ceruloplasmin is made in the liver. Ceruloplasmin stores and transports copper in the blood to parts of the body that need it.Your health care provider may order this test if you have signs or symptoms of a copper metabolism or copper storage disorder.MetabolismMetabolism refers to all the physical and chemical processes in the body that convert or use energy, such as:BreathingCirculating bloodControlling bo...ImageRead Article Now Book Mark Article Normal Results The normal range for adults is 14 to 40 mg/dL (0.93 to 2.65 µmol/L).Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or may test different samples. Talk to your provider about the meaning of your specific test results. What Abnormal Results Mean A lower-than-normal ceruloplasmin level may be due to:Long-term (chronic) liver disease Problem absorbing nutrients from food (intestinal malabsorption) Intestinal malabsorptionMalabsorption involves problems with the body's ability to take in (absorb) nutrients from food.ImageRead Article Now Book Mark Article Malnutrition MalnutritionMalnutrition is the condition that occurs when your body does not get enough nutrients.ImageRead Article Now Book Mark Article Disorder in which cells in the body can absorb copper, but are unable to release it (Menkes syndrome) Menkes syndromeMenkes disease is a genetic disorder in which the body has a problem absorbing and distributing copper to bodily organs. The disease affects develop...ImageRead Article Now Book Mark Article Group of disorders that damage the kidneys (nephrotic syndrome) Nephrotic syndromeNephrotic syndrome is a group of symptoms and abnormal test results that include protein in the urine, low blood protein levels in the blood, high ch...ImageRead Article Now Book Mark Article Inherited disorder in which there is too much copper in the body's tissues (Wilson disease)Wilson diseaseWilson disease is an inherited disorder in which there is too much copper in the body's tissues. The excess copper damages the liver and nervous sys...ImageRead Article Now Book Mark Article A higher-than-normal ceruloplasmin level may be due to:Acute and chronic infections AcuteAcute means sudden. Acute symptoms appear, change, or worsen rapidly. It is the opposite of chronic.ImageRead Article Now Book Mark Article ChronicChronic refers to something that continues over an extended period of time. A chronic condition is usually long-lasting and does not easily or quick...ImageRead Article Now Book Mark Article Cancer (breast or lymphoma) LymphomaHodgkin lymphoma is a cancer of lymph tissue. Lymph tissue is found in the lymph nodes, spleen, liver, bone marrow, and other sites.ImageRead Article Now Book Mark Article Heart disease, including heart attack Overactive thyroid Overactive thyroidHyperthyroidism is a condition in which the thyroid gland makes too much thyroid hormone. The condition is often called overactive thyroid.ImageRead Article Now Book Mark Article Pregnancy Rheumatoid arthritis Rheumatoid arthritisRheumatoid arthritis (RA) is a disease that leads to inflammation of the joints and surrounding tissues. It is a long-term disease. It can also aff...ImageRead Article Now Book Mark Article Use of birth control pills Risks There is little risk in having your blood taken. Veins and arteries vary in size from one person to another, and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others.Other risks associated with having blood drawn are slight, but may include:Excessive bleeding Fainting or feeling lightheaded Multiple punctures to locate veins Hematoma (blood accumulating under the skin) Infection (a slight risk any time the skin is broken) Open ReferencesReferencesKoppel BS. Nutritional and alcohol-related neurologic disorders. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 388.McPherson RA. Specific proteins. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Philadelphia, PA: Elsevier; 2022:chap 20.Schilsky ML. Wilson disease. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 200.AllVideoImagesTogBlood test - illustration Blood is drawn from a vein (venipuncture), usually from the inside of the elbow or the back of the hand. A needle is inserted into the vein, and the blood is collected in an air-tight vial or a syringe. Preparation may vary depending on the specific test.Blood testillustrationBlood test - illustration Blood is drawn from a vein (venipuncture), usually from the inside of the elbow or the back of the hand. A needle is inserted into the vein, and the blood is collected in an air-tight vial or a syringe. Preparation may vary depending on the specific test.Blood testillustration Tests for Ceruloplasmin blood test Ceruloplasmin blood testRelated Information Metabolism(Special Topic)Protein in diet(Nutrition)Menkes disease(Condition)Wilson disease(Condition)Hodgkin lymphoma(Condition)Acute(Special Topic)Chronic(Special Topic)Rheumatoid arthritis(Condition)Hodgkin disease - InDepth(In-Depth)Rheumatoid arthritis - InDepth(In-Depth) Review Date: 2/28/2023 Reviewed By: Jacob Berman, MD, MPH, Clinical Assistant Professor of Medicine, Division of General Internal Medicine, University of Washington School of Medicine, Seattle, WA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. 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Ceruloplasmin blood testCP - serum; Copper - ceruloplasminThe ceruloplasmin test measures the level of the copper-containing protein ceruloplasmin in the blood. How the Test is Performed A blood sample is needed. Blood sampleVenipuncture is the collection of blood from a vein. It is most often done for laboratory testing.ImageRead Article Now Book Mark Article How to Prepare for the Test No special preparation is needed. How the Test will Feel When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging. Afterward, there may be some throbbing or a slight bruise. This soon goes away. Why the Test is Performed Ceruloplasmin is made in the liver. Ceruloplasmin stores and transports copper in the blood to parts of the body that need it.Your health care provider may order this test if you have signs or symptoms of a copper metabolism or copper storage disorder.MetabolismMetabolism refers to all the physical and chemical processes in the body that convert or use energy, such as:BreathingCirculating bloodControlling bo...ImageRead Article Now Book Mark Article Normal Results The normal range for adults is 14 to 40 mg/dL (0.93 to 2.65 µmol/L).Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or may test different samples. Talk to your provider about the meaning of your specific test results. What Abnormal Results Mean A lower-than-normal ceruloplasmin level may be due to:Long-term (chronic) liver disease Problem absorbing nutrients from food (intestinal malabsorption) Intestinal malabsorptionMalabsorption involves problems with the body's ability to take in (absorb) nutrients from food.ImageRead Article Now Book Mark Article Malnutrition MalnutritionMalnutrition is the condition that occurs when your body does not get enough nutrients.ImageRead Article Now Book Mark Article Disorder in which cells in the body can absorb copper, but are unable to release it (Menkes syndrome) Menkes syndromeMenkes disease is a genetic disorder in which the body has a problem absorbing and distributing copper to bodily organs. The disease affects develop...ImageRead Article Now Book Mark Article Group of disorders that damage the kidneys (nephrotic syndrome) Nephrotic syndromeNephrotic syndrome is a group of symptoms and abnormal test results that include protein in the urine, low blood protein levels in the blood, high ch...ImageRead Article Now Book Mark Article Inherited disorder in which there is too much copper in the body's tissues (Wilson disease)Wilson diseaseWilson disease is an inherited disorder in which there is too much copper in the body's tissues. The excess copper damages the liver and nervous sys...ImageRead Article Now Book Mark Article A higher-than-normal ceruloplasmin level may be due to:Acute and chronic infections AcuteAcute means sudden. Acute symptoms appear, change, or worsen rapidly. It is the opposite of chronic.ImageRead Article Now Book Mark Article ChronicChronic refers to something that continues over an extended period of time. A chronic condition is usually long-lasting and does not easily or quick...ImageRead Article Now Book Mark Article Cancer (breast or lymphoma) LymphomaHodgkin lymphoma is a cancer of lymph tissue. Lymph tissue is found in the lymph nodes, spleen, liver, bone marrow, and other sites.ImageRead Article Now Book Mark Article Heart disease, including heart attack Overactive thyroid Overactive thyroidHyperthyroidism is a condition in which the thyroid gland makes too much thyroid hormone. The condition is often called overactive thyroid.ImageRead Article Now Book Mark Article Pregnancy Rheumatoid arthritis Rheumatoid arthritisRheumatoid arthritis (RA) is a disease that leads to inflammation of the joints and surrounding tissues. It is a long-term disease. It can also aff...ImageRead Article Now Book Mark Article Use of birth control pills Risks There is little risk in having your blood taken. Veins and arteries vary in size from one person to another, and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others.Other risks associated with having blood drawn are slight, but may include:Excessive bleeding Fainting or feeling lightheaded Multiple punctures to locate veins Hematoma (blood accumulating under the skin) Infection (a slight risk any time the skin is broken) Open ReferencesReferencesKoppel BS. Nutritional and alcohol-related neurologic disorders. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 388.McPherson RA. Specific proteins. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Philadelphia, PA: Elsevier; 2022:chap 20.Schilsky ML. Wilson disease. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 200.