BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuPorphyrins urine testUrine uroporphyrin; Urine coproporphyrin; Porphyria - uroporphyrinPorphyrins are natural chemicals in the body that help form many important substances in the body. One of these is hemoglobin, the protein in red blood cells that carries oxygen in the blood.Porphyrins can be measured in the urine or blood. This article discusses the urine test.BloodPorphyrins help form many important substances in the body. One of these is hemoglobin. This is the protein in red blood cells that carries oxygen ...ImageRead Article Now Book Mark Article How the Test is Performed After you provide a urine sample, it is tested in the lab. This is called a random urine sample.If needed, your health care provider may ask you to collect your urine at home over 24 hours. This is called a 24-hour urine sample. Your provider will tell you how to do this. Follow instructions exactly so that the results are accurate.Collect your urine at home over 24 hourThe urine 24-hour volume test measures the amount of urine produced in a day. The amounts of creatinine, protein, and other chemicals released into ...ImageRead Article Now Book Mark Article How to Prepare for the Test Your provider may tell you to temporarily stop taking medicines that may affect the test results. These may include:Antibiotics and anti-fungal drugs Anti-anxiety drugs Birth control pills Diabetes medicines Pain medicines Sleep medicinesDo not stop taking any medicine without first talking to your provider. How the Test will Feel This test involves only normal urination and there is no discomfort. Why the Test is Performed Your provider will order this test if you have signs of porphyria or other disorders that can cause abnormal urine porphyrins.PorphyriaPorphyrias are a group of rare inherited disorders. An important part of hemoglobin, called heme, is not made properly. Hemoglobin is a protein in ...ImageRead Article Now Book Mark Article Normal Results Normal results vary depending on the type of porphyrin tested. In general, for a 24-hour urine test of total porphyrins, the range is about 20 to 120 µg/L (25 to 144 nmol/L).Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or may test different specimens. Talk to your provider about the meaning of your specific test results. What Abnormal Results Mean Abnormal results may be due to:Liver cancer Liver cancerHepatocellular carcinoma is cancer that starts in the liver.ImageRead Article Now Book Mark Article Hepatitis HepatitisHepatitis is swelling and inflammation of the liver.ImageRead Article Now Book Mark Article Lead poisoning Lead poisoningLead is a very strong poison. When a person swallows an object that has lead in it or breathes in lead dust, some of the poison can stay in the body...Read Article Now Book Mark Article Porphyria (several types) Risks There are no risks with this test.Open ReferencesReferencesFuller SJ, Wiley JS. Heme biosynthesis and its disorders: porphyrias and sideroblastic anemias. In: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Basic Principles and Practice. 8th ed. Philadelphia, PA: Elsevier; 2023:chap 39.Hift RJ. The porphyrias. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 199.Riley RS, McPherson RA. Basic examination of urine. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Philadelphia, PA: Elsevier; 2022:chap 29.AllVideoImagesTogFemale urinary tract - illustration The female and male urinary tracts are relatively the same except for the length of the urethra.Female urinary tractillustrationMale urinary tract - illustration The male and female urinary tracts are relatively the same except for the length of the urethra.Male urinary tractillustrationPorphyrin urine test - illustration The uroporphyrin test measures levels of porphyrins in urine. The most important function of porphyrins is as components of heme, which is made from iron plus protoporphyrin. Hemoglobin is made up of four globin proteins plus 4 heme groups. Oxygen binds to the iron in the heme molecules. Each step requires the presence of an enzyme. If any of the enzymes are deficient because of a genetic disease or inhibition by a toxic substance, a type of porphyria results.Porphyrin urine testillustrationFemale urinary tract - illustration The female and male urinary tracts are relatively the same except for the length of the urethra.Female urinary tractillustrationMale urinary tract - illustration The male and female urinary tracts are relatively the same except for the length of the urethra.Male urinary tractillustrationPorphyrin urine test - illustration The uroporphyrin test measures levels of porphyrins in urine. The most important function of porphyrins is as components of heme, which is made from iron plus protoporphyrin. Hemoglobin is made up of four globin proteins plus 4 heme groups. Oxygen binds to the iron in the heme molecules. Each step requires the presence of an enzyme. If any of the enzymes are deficient because of a genetic disease or inhibition by a toxic substance, a type of porphyria results.Porphyrin urine testillustration Tests for Porphyrins urine test Porphyrins urine testUrine chemistryPorphyrins blood testPBG urine testRelated Information Porphyria(Condition)Hemoglobin(Medical Test)Delta-ALA urine test(Medical Test)PBG urine test(Medical Test)Enzyme(Special Topic)Liver cancer - hepatocellular carcinoma(Condition)Hepatitis(Condition)Lead poisoning(Poison)Hepatitis - InDepth(In-Depth) Review Date: 2/2/2023 Reviewed By: Mark Levin, MD, Hematologist and Oncologist, Monsey, NY. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. 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Porphyrins urine testUrine uroporphyrin; Urine coproporphyrin; Porphyria - uroporphyrinPorphyrins are natural chemicals in the body that help form many important substances in the body. One of these is hemoglobin, the protein in red blood cells that carries oxygen in the blood.Porphyrins can be measured in the urine or blood. This article discusses the urine test.BloodPorphyrins help form many important substances in the body. One of these is hemoglobin. This is the protein in red blood cells that carries oxygen ...ImageRead Article Now Book Mark Article How the Test is Performed After you provide a urine sample, it is tested in the lab. This is called a random urine sample.If needed, your health care provider may ask you to collect your urine at home over 24 hours. This is called a 24-hour urine sample. Your provider will tell you how to do this. Follow instructions exactly so that the results are accurate.Collect your urine at home over 24 hourThe urine 24-hour volume test measures the amount of urine produced in a day. The amounts of creatinine, protein, and other chemicals released into ...ImageRead Article Now Book Mark Article How to Prepare for the Test Your provider may tell you to temporarily stop taking medicines that may affect the test results. These may include:Antibiotics and anti-fungal drugs Anti-anxiety drugs Birth control pills Diabetes medicines Pain medicines Sleep medicinesDo not stop taking any medicine without first talking to your provider. How the Test will Feel This test involves only normal urination and there is no discomfort. Why the Test is Performed Your provider will order this test if you have signs of porphyria or other disorders that can cause abnormal urine porphyrins.PorphyriaPorphyrias are a group of rare inherited disorders. An important part of hemoglobin, called heme, is not made properly. Hemoglobin is a protein in ...ImageRead Article Now Book Mark Article Normal Results Normal results vary depending on the type of porphyrin tested. In general, for a 24-hour urine test of total porphyrins, the range is about 20 to 120 µg/L (25 to 144 nmol/L).Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or may test different specimens. Talk to your provider about the meaning of your specific test results. What Abnormal Results Mean Abnormal results may be due to:Liver cancer Liver cancerHepatocellular carcinoma is cancer that starts in the liver.ImageRead Article Now Book Mark Article Hepatitis HepatitisHepatitis is swelling and inflammation of the liver.ImageRead Article Now Book Mark Article Lead poisoning Lead poisoningLead is a very strong poison. When a person swallows an object that has lead in it or breathes in lead dust, some of the poison can stay in the body...Read Article Now Book Mark Article Porphyria (several types) Risks There are no risks with this test.Open ReferencesReferencesFuller SJ, Wiley JS. Heme biosynthesis and its disorders: porphyrias and sideroblastic anemias. In: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Basic Principles and Practice. 8th ed. Philadelphia, PA: Elsevier; 2023:chap 39.Hift RJ. The porphyrias. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 199.Riley RS, McPherson RA. Basic examination of urine. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Philadelphia, PA: Elsevier; 2022:chap 29.