BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuPBG urine testPorphobilinogen test; Porphyria - urine; PBGPorphobilinogen (PBG) is one of several types of porphyrins found in your body. Porphyrins help form many important substances in the body. One of these is hemoglobin, the protein in red blood cells that carries oxygen in the blood. Porphyrins usually leave your body through urine or stools. If this process does not occur, porphyrins such as PBG can build up in your body.This article describes the test to measure the amount of PBG in a urine sample. How the Test is Performed After you provide a urine sample, it is tested in the lab. This is called a random urine sample. If needed, your health care provider may ask you to collect your urine at home over 24 hours. This is called a 24-hour urine sample. Your provider will tell you how to do this. Follow instructions exactly.Collect your urine at home over 24 hourThe urine 24-hour volume test measures the amount of urine produced in a day. The amounts of creatinine, protein, and other chemicals released into ...ImageRead Article Now Book Mark Article How to Prepare for the Test Your provider may tell you to temporarily stop taking medicines that may affect the test results. Be sure to tell your provider about all the medicines you take. These include:Antibiotics and anti-fungal drugs Anti-anxiety drugs Birth control pills Diabetes medicines Pain medicines Sleep medicines Never stop taking any medicine without first talking to your provider. How the Test will Feel This test involves only normal urination, and there is no discomfort. Why the Test is Performed This test may be done if your provider suspects porphyria or another disorder associated with an abnormal PBG level. PorphyriaPorphyrias are a group of rare inherited disorders. An important part of hemoglobin, called heme, is not made properly. Hemoglobin is a protein in ...ImageRead Article Now Book Mark Article Normal Results For a random urine sample, a negative test result is considered normal.If the test is done on a 24-hour urine sample, the normal value is less than 4 milligrams per 24 hours (18 micromoles per 24 hours).Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or may test different specimens. Talk to your provider about the meaning of your specific test results. What Abnormal Results Mean An increased level of PBG in the urine may be due to:Hepatitis HepatitisHepatitis is swelling and inflammation of the liver.ImageRead Article Now Book Mark Article Lead poisoning Lead poisoningLead is a very strong poison. When a person swallows an object that has lead in it or breathes in lead dust, some of the poison can stay in the body...Read Article Now Book Mark Article Liver cancer Liver cancerHepatocellular carcinoma is cancer that starts in the liver.ImageRead Article Now Book Mark Article Porphyria (several types) Risks There are no risks with this test.Open ReferencesReferencesFogazzi GB, Garigali G. Urinalysis. In: Feehally J, Floege J, Tonelli M, Johnson RJ, eds. Comprehensive Clinical Nephrology. 6th ed. Philadelphia, PA: Elsevier; 2019:chap 4.Fuller SJ, Wiley JS. Heme biosynthesis and its disorders: porphyrias and sideroblastic anemias. In: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Basic Principles and Practice. 8th ed. Philadelphia, PA: Elsevier; 2023:chap 39.Riley RS, McPherson RA. Basic examination of urine. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Philadelphia, PA: Elsevier; 2022:chap 29.AllVideoImagesTogMale urinary system - illustration The urinary system is made up of the kidneys, ureters, urethra and bladder.Male urinary systemillustrationMale urinary system - illustration The urinary system is made up of the kidneys, ureters, urethra and bladder.Male urinary systemillustration Tests for PBG urine test PBG urine testRelated Information Porphyria(Condition)Hemoglobin(Medical Test)Delta-ALA urine test(Medical Test)Porphyrins urine test(Medical Test)Liver cancer - hepatocellular carcinoma(Condition)Hepatitis(Condition)Lead poisoning(Poison)Hepatitis - InDepth(In-Depth) Review Date: 2/2/2023 Reviewed By: Mark Levin, MD, Hematologist and Oncologist, Monsey, NY. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. 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PBG urine testPorphobilinogen test; Porphyria - urine; PBGPorphobilinogen (PBG) is one of several types of porphyrins found in your body. Porphyrins help form many important substances in the body. One of these is hemoglobin, the protein in red blood cells that carries oxygen in the blood. Porphyrins usually leave your body through urine or stools. If this process does not occur, porphyrins such as PBG can build up in your body.This article describes the test to measure the amount of PBG in a urine sample. How the Test is Performed After you provide a urine sample, it is tested in the lab. This is called a random urine sample. If needed, your health care provider may ask you to collect your urine at home over 24 hours. This is called a 24-hour urine sample. Your provider will tell you how to do this. Follow instructions exactly.Collect your urine at home over 24 hourThe urine 24-hour volume test measures the amount of urine produced in a day. The amounts of creatinine, protein, and other chemicals released into ...ImageRead Article Now Book Mark Article How to Prepare for the Test Your provider may tell you to temporarily stop taking medicines that may affect the test results. Be sure to tell your provider about all the medicines you take. These include:Antibiotics and anti-fungal drugs Anti-anxiety drugs Birth control pills Diabetes medicines Pain medicines Sleep medicines Never stop taking any medicine without first talking to your provider. How the Test will Feel This test involves only normal urination, and there is no discomfort. Why the Test is Performed This test may be done if your provider suspects porphyria or another disorder associated with an abnormal PBG level. PorphyriaPorphyrias are a group of rare inherited disorders. An important part of hemoglobin, called heme, is not made properly. Hemoglobin is a protein in ...ImageRead Article Now Book Mark Article Normal Results For a random urine sample, a negative test result is considered normal.If the test is done on a 24-hour urine sample, the normal value is less than 4 milligrams per 24 hours (18 micromoles per 24 hours).Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or may test different specimens. Talk to your provider about the meaning of your specific test results. What Abnormal Results Mean An increased level of PBG in the urine may be due to:Hepatitis HepatitisHepatitis is swelling and inflammation of the liver.ImageRead Article Now Book Mark Article Lead poisoning Lead poisoningLead is a very strong poison. When a person swallows an object that has lead in it or breathes in lead dust, some of the poison can stay in the body...Read Article Now Book Mark Article Liver cancer Liver cancerHepatocellular carcinoma is cancer that starts in the liver.ImageRead Article Now Book Mark Article Porphyria (several types) Risks There are no risks with this test.Open ReferencesReferencesFogazzi GB, Garigali G. Urinalysis. In: Feehally J, Floege J, Tonelli M, Johnson RJ, eds. Comprehensive Clinical Nephrology. 6th ed. Philadelphia, PA: Elsevier; 2019:chap 4.Fuller SJ, Wiley JS. Heme biosynthesis and its disorders: porphyrias and sideroblastic anemias. In: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Basic Principles and Practice. 8th ed. Philadelphia, PA: Elsevier; 2023:chap 39.Riley RS, McPherson RA. Basic examination of urine. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Philadelphia, PA: Elsevier; 2022:chap 29.