E-mail Form
Email Results

 
 
Print-Friendly
Bookmarks
bookmarks-menu

Lipase test

Pancreatitis - blood lipase

Lipase is a protein (enzyme) released by the pancreas into the small intestine. It helps the body absorb fat. This test is used to measure the amount of lipase in the blood.

How the Test is Performed

A sample of blood will be taken from a vein.

How to Prepare for the Test

Do not eat for 8 hours before the test.

Your health care provider may ask you to stop taking medicines that may affect the test, such as:

  • Birth control pills
  • Cholinergic medicines
  • Indomethacin
  • Opiates (codeine, meperidine, and morphine)
  • Thiazide diuretics

How the Test will Feel

You may feel slight pain or a sting when the needle is inserted to draw blood. There may be some throbbing at the site after the blood is drawn. Veins and arteries vary in size, so it may be harder to take a blood sample from one person than another.

Why the Test is Performed

This test is done to check for disease of the pancreas, most often acute pancreatitis.

Lipase appears in excessive amounts in the blood when the pancreas is damaged.

Normal Results

In general, normal results are 0 to 160 units per liter (U/L) or 0 to 2.67 microkat/L (µkat/L).

Normal value ranges may vary slightly among different laboratories. Some laboratories use different measurement methods. Talk to your provider about the meaning of your test results.

What Abnormal Results Mean

Higher-than-normal levels may be due to:

This test may also be done for familial lipoprotein lipase deficiency.

Risks

There is very little risk from your blood taken.

Other uncommon risks may include:

  • Bleeding from the needle puncture site
  • Fainting or feeling lightheaded
  • Blood collecting under the skin
  • Infection (a slight risk any time the skin is broken)

References

Crockett SD, Wani S, Gardner TB, Falck-Ytter Y, Barkun AN; American Gastroenterological Association Institute Clinical Guidelines Committee. American Gastroenterological Association Institute guideline on initial management of acute pancreatitis. Gastroenterology. 2018;154(4):1096-1101. PMID: 29409760 pubmed.ncbi.nlm.nih.gov/29409760/.

Forsmark CE. Pancreatitis. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 135.

Siddiqi HA, Rabinowitz S, Axiotis CA. Laboratory diagnosis of gastrointestinal and pancreatic disorders. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Philadelphia, PA: Elsevier; 2022:chap 23.

Vege SS. Acute pancreatitis. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 11th ed. Philadelphia, PA: Elsevier; 2021:chap 58.

Text only

  • Blood test

    Blood test - illustration

    Blood is drawn from a vein (venipuncture), usually from the inside of the elbow or the back of the hand. A needle is inserted into the vein, and the blood is collected in an air-tight vial or a syringe. Preparation may vary depending on the specific test.

    Blood test

    illustration

    • Blood test

      Blood test - illustration

      Blood is drawn from a vein (venipuncture), usually from the inside of the elbow or the back of the hand. A needle is inserted into the vein, and the blood is collected in an air-tight vial or a syringe. Preparation may vary depending on the specific test.

      Blood test

      illustration

    Tests for Lipase test

     
     

    Review Date: 2/28/2023

    Reviewed By: Jacob Berman, MD, MPH, Clinical Assistant Professor of Medicine, Division of General Internal Medicine, University of Washington School of Medicine, Seattle, WA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

    The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. No warranty of any kind, either expressed or implied, is made as to the accuracy, reliability, timeliness, or correctness of any translations made by a third-party service of the information provided herein into any other language. © 1997- A.D.A.M., a business unit of Ebix, Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
    © 1997- adam.comAll rights reserved.

     
     
     

     

     

    A.D.A.M. content is best viewed in IE9 or above, Firefox and Google Chrome browser.
    Content is best viewed in IE9 or above, Firefox and Google Chrome browser.

    Select Location