MalaiseGeneral ill feeling
Malaise is a general feeling of discomfort, illness, or lack of well-being.
Malaise is a symptom that can occur with almost any health condition. It may start slowly or quickly, depending on the type of disease.
Fatigue (feeling tired) occurs with malaise in many diseases. You can have a feeling of not having enough energy to do your usual activities.
Fatigue is a feeling of weariness, tiredness, or lack of energy.Read Article Now Book Mark Article
The following lists give examples of the diseases, conditions, and medicines that can cause malaise.
SHORT-TERM (ACUTE) INFECTIOUS DISEASE
- Acute bronchitis or pneumonia
Pneumonia is a breathing (respiratory) condition in which there is an infection of the lung. This article covers community-acquired pneumonia (CAP). ...Read Article Now Book Mark Article
- Acute viral syndrome
- Infectious mononucleosis (EBV)
Mononucleosis, or mono, is a viral infection that causes fever, sore throat, and swollen lymph glands, most often in the neck.Read Article Now Book Mark Article
The flu is an infection of the nose, throat, and lungs. It spreads easily from person to person. This article discusses influenza types A and B. A ...Read Article Now Book Mark Article
- Lyme disease
Lyme disease is a bacterial infection that is spread through the bite of one of several types of ticks.Read Article Now Book Mark Article
LONG-TERM (CHRONIC) INFECTIOUS DISEASE
Human immunodeficiency virus (HIV) is the virus that causes acquired immunodeficiency syndrome (AIDS). When a person becomes infected with HIV, the ...Read Article Now Book Mark Article
- Chronic active hepatitis
Hepatitis is swelling and inflammation of the liver.Read Article Now Book Mark Article
- Disease caused by parasites
Pulmonary tuberculosis (TB) is a contagious bacterial infection that involves the lungs. It may spread to other organs.Read Article Now Book Mark Article
HEART AND LUNG (CARDIOPULMONARY) DISEASE
- Congestive heart failure
Congestive heart failure
Heart failure is a condition in which the heart is no longer able to pump oxygen-rich blood to the rest of the body efficiently. This causes symptom...Read Article Now Book Mark Article
Chronic obstructive pulmonary disease (COPD) is a common lung disease. Having COPD makes it hard to breathe. There are two main forms of COPD:Chroni...Read Article Now Book Mark Article
- Acute or chronic kidney disease
- Acute or chronic liver disease
The term "liver disease" applies to many conditions that stop the liver from working or prevent it from functioning well. Abdominal pain or swelling...Read Article Now Book Mark Article
CONNECTIVE TISSUE DISEASE
- Rheumatoid arthritis
Rheumatoid arthritis (RA) is a disease that leads to inflammation of the joints and surrounding tissues. It is a long-term disease. It can also aff...Read Article Now Book Mark Article
Sarcoidosis is a disease in which inflammation occurs in the lymph nodes, lungs, liver, eyes, skin, and/or other tissues.Read Article Now Book Mark Article
- Systemic lupus erythematosus
Systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is an autoimmune disease. In this disease, the immune system of the body mistakenly attacks healthy tissue. It c...Read Article Now Book Mark Article
ENDOCRINE or METABOLIC DISEASE
- Adrenal gland dysfunction
The adrenal glands are two small triangle-shaped glands in the upper abdomen. One gland is located on top of each kidney.Read Article Now Book Mark Article
Diabetes is a long-term (chronic) disease in which the body cannot regulate the amount of sugar in the blood.Read Article Now Book Mark Article
- Pituitary gland dysfunction (rare)
- Thyroid disease
Leukemia is a type of blood cancer that begins in the bone marrow. Bone marrow is the soft tissue in the center of the bones, where blood cells are ...Read Article Now Book Mark Article
- Lymphoma (cancer that starts in the lymph system)
The lymph system is a network of organs, lymph nodes, lymph ducts, and lymph vessels that make and move lymph from tissues to the bloodstream. The l...Read Article Now Book Mark Article
- Solid tumor cancers, such as colon cancer
Colorectal cancer is cancer that starts in the large intestine (colon) or the rectum (end of the colon). Other types of cancer can affect the colon. ...Read Article Now Book Mark Article
- Severe anemia
Anemia is a condition in which the body does not have enough healthy red blood cells. Red blood cells provide oxygen to body tissues. Different type...Read Article Now Book Mark Article
Depression is feeling sad, blue, unhappy, or down in the dumps. Most people feel this way once in a while. Major depression is a mood disorder. It...Read Article Now Book Mark Article
Persistent depressive disorder (PDD) is a chronic (ongoing) type of depression in which a person's moods are regularly low. Persistent depressive dis...Read Article Now Book Mark Article
- Anticonvulsant (antiseizure) medicines
- Beta blockers (medicines used to treat heart disease or high blood pressure)
- Psychiatric medicines
- Treatments involving several medicines
Call your health care provider right away if you have severe malaise.
When to Contact a Medical Professional
Call your provider if:
- You have other symptoms with the malaise
- Malaise lasts longer than one week, with or without other symptoms
What to Expect at Your Office Visit
Your provider will perform a physical exam and ask questions such as:
- How long has this feeling lasted (weeks or months)?
- What other symptoms do you have?
- Is the malaise constant or episodic (comes and goes)?
- Can you complete your daily activities? If not, what limits you?
- Have you traveled recently?
- What medicines are you on?
- What are your other medical problems?
- Do you use alcohol or other drugs?
You may have tests to confirm the diagnosis if your provider thinks the problem may be due to an illness. These may include blood tests, x-rays, or other diagnostic tests.
Your provider will recommend treatment if needed based on your exam and tests.
Leggett JE. Approach to fever or suspected infection in the normal host. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 264.
Nield LS, Kamat D. Fever. In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Textbook of Pediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020:chap 201.
Simel DL. Approach to the patient: history and physical examination. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 6.
Review Date: 1/16/2021
Reviewed By: Linda J. Vorvick, MD, Clinical Associate Professor, Department of Family Medicine, UW Medicine, School of Medicine, University of Washington, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.