Stroke
Cerebrovascular disease; CVA; Cerebral infarction; Cerebral hemorrhage; Ischemic stroke; Stroke - ischemic; Cerebrovascular accident; Stroke - hemorrhagic; Carotid artery - strokeA stroke occurs when blood flow to a part of the brain stops. A stroke is sometimes called a "brain attack."
If blood flow is cut off for longer than a few seconds, the brain cannot get nutrients and oxygen. Brain cells can die, causing lasting damage.
A stroke can also occur if a blood vessel inside the brain bursts, leading to bleeding inside the head.
Causes
There are two major types of stroke:
- Ischemic stroke
- Hemorrhagic stroke
Ischemic stroke occurs when a blood vessel that supplies blood to the brain is blocked by a blood clot. This may happen in two ways:
- A clot may form in an artery that is already very narrow. This is called a thrombotic stroke.
- A clot may break off from another place in the blood vessels of the brain, or from some other part of the body, and travel up to the brain. This is called cerebral embolism, or an embolic stroke.
Ischemic strokes may also be caused by a sticky substance called plaque that can clog arteries.
A hemorrhagic stroke occurs when a blood vessel in part of the brain becomes weak and bursts open. This causes blood to leak into the brain. Some people have defects in the blood vessels of the brain that make this more likely. These defects may include:
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Aneurysm (weak area in the wall of a blood vessel that causes the blood vessel to bulge or balloon out)
Aneurysm
An aneurysm is a weak area in the wall of a blood vessel that causes the blood vessel to bulge or balloon out. When an aneurysm occurs in a blood ve...
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Arteriovenous malformation (AVM; abnormal connection between the arteries and veins)
Arteriovenous malformation
A cerebral arteriovenous malformation (AVM) is an abnormal connection between the arteries and veins in the brain that usually forms before birth....
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Cerebral amyloid angiopathy (CAA; condition in which proteins called amyloid build up on the walls of the arteries in the brain)
Cerebral amyloid angiopathy
Cerebral amyloid angiopathy (CAA) is a condition in which proteins called amyloid build up on the walls of the arteries in the brain. CAA causes ble...
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Hemorrhagic strokes may also occur when someone is taking blood thinners, such as dabigatran, rivaroxaban, apixaban, edoxaban and warfarin (Coumadin) or has a bleeding disorder. Very high blood pressure may cause blood vessels to burst, leading to hemorrhagic stroke.
An ischemic stroke can develop bleeding and become a hemorrhagic stroke.
High blood pressure is the main risk factor for strokes. Other major risk factors are:
High blood pressure
Blood pressure is a measurement of the force exerted against the walls of your arteries as your heart pumps blood to your body. Hypertension is the ...
Read Article Now Book Mark ArticleRisk factor for strokes
A stroke occurs when blood flow to a part of the brain suddenly stops. A stroke is sometimes called a "brain attack or cerebrovascular accident. " I...
Read Article Now Book Mark Article- Irregular heartbeat, called atrial fibrillation
Atrial fibrillation
Atrial fibrillation (Afib) and atrial flutter are common types of abnormal heart rhythms (arrhythmias) which affect the upper chambers (atria) of the...
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Diabetes
Diabetes
Diabetes is a long-term (chronic) disease in which the body cannot regulate the amount of sugar in the blood.
Read Article Now Book Mark Article - Family history of stroke
- Being male
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High cholesterol
High cholesterol
Cholesterol is a fat (also called a lipid) that your body needs to work properly. Too much bad cholesterol in your blood can increase your chance of...
Read Article Now Book Mark Article - Increasing age, especially after age 55
- Ethnicity (African Americans are more likely to die of a stroke)
- Obesity
- History of prior stroke or transient ischemic attack (occurs when blood flow to a part of the brain stops for a brief time)
Transient ischemic attack
A transient ischemic attack (TIA) occurs when blood flow to a part of the brain stops for a brief time. A person will have stroke-like symptoms for ...
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Stroke risk is also higher in:
- People who have heart disease or poor blood flow in their legs caused by narrowed arteries
Poor blood flow in their legs
Peripheral artery disease (PAD) is a condition of the blood vessels that supply the legs and feet. It occurs due to narrowing of the arteries in the...
Read Article Now Book Mark Article - People who have unhealthy lifestyle habits such as smoking, excessive use of alcohol, use recreational drugs, a high-fat diet, or lack of exercise
Unhealthy lifestyle
Good health habits can allow you to avoid illness and improve your quality of life. The following steps will help you feel better and live better. G...
Read Article Now Book Mark Article - People who have a hereditary tendency to develop blood clots
- Women who take birth control pills (especially those who smoke and are older than 35)
- Women who are pregnant have an increased risk while pregnant
- Women who take hormone replacement therapy
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Patent foramen ovale (PFO), a hole between the left and right atria (upper chambers) of the heart
Patent foramen ovale (PFO)
Patent foramen ovale (PFO) is a hole between the left and right atria (upper chambers) of the heart. This hole exists in everyone before birth, but ...
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Symptoms
Symptoms of stroke depend on which part of the brain is damaged. In some cases, a person may not know that a stroke has occurred.
Most of the time, symptoms develop suddenly and without warning. But symptoms may occur on and off for the first day or two. Symptoms are usually most severe when the stroke first happens, but they may slowly get worse.
Cerebellum - function
The cerebellum processes input from other areas of the brain, spinal cord and sensory receptors to provide precise timing for coordinated, smooth movements of the skeletal muscular system. A stroke affecting the cerebellum may cause dizziness, nausea, balance and coordination problems.
A headache may occur if the stroke is caused by bleeding in the brain. The headache:
- Starts suddenly and may be severe
- May be worse when you are lying flat
- May wake you up from sleep
- May get worse when you change positions or when you bend, strain, or cough
Brainstem function
A stroke affecting the brain stem is potentially life threatening since this area of the brain controls functions such as breathing and instructing the heart to beat. Brain stem stroke may also cause double vision, nausea and loss of coordination. The brain stem also controls less essential abilities such as articulate speech.
Other symptoms depend on how severe the stroke is, and what part of the brain is affected. Symptoms may include:
- Change in alertness (including sleepiness, unconsciousness, and coma)
- Changes in hearing or taste
- Changes that affect touch and the ability to feel pain, pressure, or different temperatures
- Confusion or loss of memory
- Problems swallowing
- Problems writing or reading
- Dizziness or abnormal feeling of movement (vertigo)
- Eyesight problems, such as decreased vision, double vision, or total loss of vision
- Lack of control over the bladder or bowels
- Loss of balance or coordination, or trouble walking
- Muscle weakness in the face, arm, or leg (usually just on one side)
- Numbness or tingling on one side of the body
- Personality, mood, or emotional changes
- Trouble speaking or understanding others who are speaking
Exams and Tests
Your health care provider will do a physical exam to:
- Check for problems with vision, movement, feeling, reflexes, understanding, and speaking. Your provider and nurses will repeat this exam over time to see if your stroke is getting worse or improving.
- Listen to the carotid arteries in the neck with a stethoscope for an abnormal sound, called a bruit, which is caused by abnormal blood flow.
- Check for high blood pressure and an irregular heartbeat.
Carotid stenosis - X-ray of the left artery
A carotid arteriogram is an X-ray study designed to determine if there is narrowing or other abnormality in the carotid artery, a main artery to the brain. This is an angiogram of the left common carotid artery (both front-to-back and side views) showing a severe narrowing (stenosis) of the internal carotid artery just beyond the division of the common carotid artery into the internal and external branches.
You may have the following tests to help find the type, location, and cause of the stroke and rule out other problems:
- CT scan of the brain to determine if there is any bleeding
- MRI of the brain to determine the location of the stroke
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Angiogram of the head to look for a blood vessel that is blocked or bleeding
Angiogram of the head
Cerebral angiography is a procedure that uses a special dye (contrast material) and x-rays to see how blood flows through the brain.
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Carotid duplex (ultrasound) to see if the carotid arteries in your neck have narrowed
Carotid duplex
Carotid duplex is an ultrasound test that shows how well blood is flowing through the carotid arteries. The carotid arteries are located in the neck...
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Echocardiogram to see if the stroke could have been caused by a blood clot from the heart
Echocardiogram
An echocardiogram is a test that uses sound waves to create pictures of the heart. The picture and information it produces is more detailed than a s...
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Magnetic resonance angiography (MRA) or CT angiography to check for abnormal blood vessels in the brain
Magnetic resonance angiography
Magnetic resonance angiography (MRA) is an MRI exam of the blood vessels. Unlike traditional angiography that involves placing a tube (catheter) int...
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Other tests include:
- Blood tests
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Electroencephalogram (EEG) to determine if there are seizures
Electroencephalogram
An electroencephalogram (EEG) is a test to measure the electrical activity of the brain.
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Electrocardiogram (ECG) and heart rhythm monitoring
Electrocardiogram
An electrocardiogram (ECG) is a test that records the electrical activity of the heart.
Read Article Now Book Mark ArticleHeart rhythm monitoring
A Holter monitor is a machine that continuously records the heart's rhythms. The monitor is worn for 24 to 48 hours during normal activity.
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Treatment
A stroke is a medical emergency. Quick treatment is needed. Call 911 or the local emergency number right away or seek urgent medical care at the first signs of a stroke.
People who are having stroke symptoms need to get to a hospital as quickly as possible.
- If the stroke is caused by a blood clot, a clot-busting medicine may be given to dissolve the clot.
- To be effective, this treatment must be started within 4 1/2 hours of when the symptoms first started. However, the sooner this treatment is started, the better the chance of a good outcome.
- Endovascular thrombectomy may be needed. This is when a catheter is inserted into your arteries. Dye is injected while images of your brain's blood vessels are reviewed. A clot, if found, could be removed through the catheter.
Other treatments given in the hospital depend on the cause of the stroke. These may include:
- Blood thinners such as heparin, warfarin (Coumadin), direct acting oral anticoagulants (DOACs), aspirin, or clopidogrel (Plavix)
- Medicine to control risk factors, such as high blood pressure, diabetes, and high cholesterol
- Special procedures or surgery to relieve symptoms or prevent more strokes
- Nutrients and fluids
Physical therapy, occupational therapy, speech therapy, and swallowing therapy will all begin in the hospital. If the person has severe swallowing problems, a feeding tube in the stomach (gastrostomy tube) will likely be needed.
The goal of treatment after a stroke is to help you recover as much function as possible and prevent future strokes.
Recovery from your stroke will begin while you are still in the hospital or at a rehabilitation center. It will continue when you go home from the hospital or center. Be sure to follow up with your provider after you go home.
Recovery
A stroke happens when blood flow to any part of the brain stops. Each person has a different recovery time and need for long-term care. Problems wit...
Read Article Now Book Mark ArticleSupport Groups
More information and support for people with stroke and their families can be found on the American Stroke Association website -- www.stroke.org/en/help-and-support.
Outlook (Prognosis)
How well a person does after a stroke depends on:
- The type of stroke
- How much brain tissue is damaged
- What body functions have been affected
- How quickly treatment is given
Problems moving, thinking, and talking often start to improve in the days to weeks after a stroke.
Many people develop depression after a stroke. This can slow down recovery but is also a very treatable complication of a stroke.
Depression
Depression may be described as feeling sad, blue, unhappy, miserable, or down in the dumps. Most of us feel this way at one time or another for shor...
Read Article Now Book Mark ArticleMany people who have had a stroke will keep improving in the months or years after their stroke.
Over half of people who have a stroke are able to function and live at home. Others are not able to care for themselves.
If treatment with clot-busting medicines is successful, the symptoms of a stroke may go away. However, people often do not get to the hospital soon enough to receive these medicines, or they cannot take these medicines because of a health condition.
People who have a stroke from a blood clot (ischemic stroke) have a better chance of surviving than those who have a stroke from bleeding in the brain (hemorrhagic stroke).
The risk for a second stroke is highest during the weeks or months after the first stroke. The risk begins to decrease after this period.
When to Contact a Medical Professional
Stroke is a medical emergency that needs to be treated right away. The acronym F.A.S.T. is an easy way to remember signs of stroke and what to do if you think a stroke has occurred. The most important action to take is to call 911 or the local emergency number right away for emergency assistance.
F.A.S.T. stands for:
- FACE. Ask the person to smile. Check if one side of the face droops.
- ARMS. Ask the person to raise both arms. See if one arm drifts downward.
- SPEECH. Ask the person to repeat a simple sentence. Check if words are slurred and if the sentence is repeated correctly.
- TIME. If a person shows any of these symptoms, time is essential. It is important to get to the hospital as quickly as possible. Call 911 or the local emergency number. Act F.A.S.T.
Prevention
Reducing your stroke risk factors lessens your chance of having a stroke.
Risk factors
A stroke occurs when blood flow to a part of the brain suddenly stops. A stroke is sometimes called a "brain attack or cerebrovascular accident. " I...
Read Article Now Book Mark ArticleReferences
Biller J, Schneck MJ, Ruland S. Ischemic cerebrovascular disease. In Jankovic J, Mazziotta JC, Pomeroy SL, Newman NJ, eds. Bradley's and Daroff's Neurology in Clinical Practice. 8th ed. Philadelphia, PA: Elsevier; 2022:chap 65.
Gladstone DJ, Lindsay MP, Douketis J, et al. Canadian stroke consortium. Canadian stroke best practice recommendations: secondary prevention of stroke Update 2020. Can J Neurol Sci. 2022;49(3):315-337. PMID: 34140063 pubmed.ncbi.nlm.nih.gov/34140063/.
Grundy SM, Stone NJ, Bailey AL, et al. 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the management of blood cholesterol: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. J Am Coll Cardiol. 2019;73(24):3234-3237. PMID: 30423391 pubmed.ncbi.nlm.nih.gov/30423391/.
January CT, Wann LS, Calkins H, et al. 2019 AHA/ACC/HRS focused updated of the 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on practice guidelines and the Heart Rhythm Society. J Am Coll Cardiol. 2019;74(1):104-132. PMID: 30703431 pubmed.ncbi.nlm.nih.gov/30703431/.
Kleindorfer DO, Towfighi A, Chaturvedi S, et al. 2021 Guideline for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline from the American Heart Association/American Stroke Association. Stroke. 2021;52(7)e-364-e467. PMID: 34024117 pubmed.ncbi.nlm.nih.gov/34024117/.
Meschia JF, Bushnell C, Boden-Albala B, et al. Guidelines for the primary prevention of stroke: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2014;45(12):3754-3832. PMID: 25355838 pubmed.ncbi.nlm.nih.gov/25355838/.
Papa L, Meurer WJ. Stroke. In: Walls RM, ed. Rosen's Emergency Medicine: Concepts and Clinical Practice. 10th ed. Philadelphia, PA: Elsevier; 2023:chap 87.
Powers WJ, Rabinstein AA, Ackerson T, et al. Guidelines for the early management of patients with acute ischemic stroke: 2019 update to the 2018 guidelines for the early management of acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2019;50(12):e344-e418. PMID: 31662037 pubmed.ncbi.nlm.nih.gov/31662037/.
Riegel B, Moser DK, Buck HG, et al; American Heart Association Council on Cardiovascular and Stroke Nursing; Council on Peripheral Vascular Disease; and Council on Quality of Care and Outcomes Research. Self-care for the prevention and management of cardiovascular disease and stroke: a scientific statement for healthcare professionals from the American Heart Association. J Am Heart Assoc. 2017;6(9).e006997. PMID: 28860232 pubmed.ncbi.nlm.nih.gov/28860232/.
Whelton PK, Carey RM, Aronow WS, et al. 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. J Am Coll Cardiol. 2018;72(3):e127-e248. PMID: 29133354 pubmed.ncbi.nlm.nih.gov/29133354/.
Winstein CJ, Stein J, Arena R, et al. Guidelines for adult stroke rehabilitation and recovery: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2016;47(6):e98-e169. PMID: 27145936 pubmed.ncbi.nlm.nih.gov/27145936/.
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Stroke
Animation
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Stroke
Animation
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Brain - illustration
The major areas of the brain have one or more specific functions.
Brain
illustration
-
Carotid stenosis - X-ray of the left artery - illustration
A carotid arteriogram is an X-ray study designed to determine if there is narrowing or other abnormality in the carotid artery, a main artery to the brain. This is an angiogram of the left common carotid artery (both front-to-back and side views) showing a severe narrowing (stenosis) of the internal carotid artery just beyond the division of the common carotid artery into the internal and external branches.
Carotid stenosis - X-ray of the left artery
illustration
-
Carotid stenosis - X-ray of the right artery - illustration
This is an angiogram of the right carotid artery showing a severe narrowing (stenosis) of the internal carotid artery just past the carotid fork. There is enlargement of the artery or ulceration in the area after the stenosis in this close-up film. Note the narrowed segment toward the bottom of the picture.
Carotid stenosis - X-ray of the right artery
illustration
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Stroke - illustration
A stroke involves loss of brain functions caused by a loss of blood circulation to areas of the brain. The blockage usually occurs when a clot or piece of atherosclerotic plaque breaks away from another area of the body and lodges within the vasculature of the brain.
Stroke
illustration
-
Brainstem function - illustration
A stroke affecting the brain stem is potentially life threatening since this area of the brain controls functions such as breathing and instructing the heart to beat. Brain stem stroke may also cause double vision, nausea and loss of coordination. The brain stem also controls less essential abilities such as articulate speech.
Brainstem function
illustration
-
Cerebellum - function - illustration
The cerebellum processes input from other areas of the brain, spinal cord and sensory receptors to provide precise timing for coordinated, smooth movements of the skeletal muscular system. A stroke affecting the cerebellum may cause dizziness, nausea, balance and coordination problems.
Cerebellum - function
illustration
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Circle of Willis - illustration
The Circle of Willis is the joining area of several arteries at the bottom (inferior) side of the brain. At the Circle of Willis, the internal carotid arteries branch into smaller arteries that supply oxygenated blood to over 80% of the cerebrum.
Circle of Willis
illustration
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Left cerebral hemisphere - function - illustration
The left cerebral hemisphere controls movement of the right side of the body. Depending on the severity, a stroke affecting the left cerebral hemisphere may result in functional loss or motor skill impairment of the right side of the body, and may also cause loss of speech.
Left cerebral hemisphere - function
illustration
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Right cerebral hemisphere - function - illustration
The right cerebral hemisphere controls movement of the left side of the body. Depending on the severity, a stroke affecting the right cerebral hemisphere may result in functional loss or motor skill impairment of the left side of the body. In addition, there may be impairment of the normal attention to the left side of the body and its surroundings.
Right cerebral hemisphere - function
illustration
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Endarterectomy - illustration
Endarterectomy is a surgical procedure removing plaque material from the lining of an artery.
Endarterectomy
illustration
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Plaque buildup in arteries - illustration
A heart attack or stroke may occur when an area of plaque (atherosclerosis) ruptures and a clot forms over the location, blocking the flow of blood to the organ's tissues.
Plaque buildup in arteries
illustration
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Stroke - Series
Presentation
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Carotid dissection - illustration
Stroke is defined as a loss of brain function due to blocked blood circulation to the brain. Strokes may be caused by a narrowing, obstruction, or leak in the lining of the carotid. This leaking of blood into the artery wall (dissection) may cause a clot to form, reducing blood flow and raising the risk of a stroke. The leak may arise from an injury to the neck, which means stroke secondary to carotid dissection may occur in young people as well as older people.
Carotid dissection
illustration
-
Brain - illustration
The major areas of the brain have one or more specific functions.
Brain
illustration
-
Carotid stenosis - X-ray of the left artery - illustration
A carotid arteriogram is an X-ray study designed to determine if there is narrowing or other abnormality in the carotid artery, a main artery to the brain. This is an angiogram of the left common carotid artery (both front-to-back and side views) showing a severe narrowing (stenosis) of the internal carotid artery just beyond the division of the common carotid artery into the internal and external branches.
Carotid stenosis - X-ray of the left artery
illustration
-
Carotid stenosis - X-ray of the right artery - illustration
This is an angiogram of the right carotid artery showing a severe narrowing (stenosis) of the internal carotid artery just past the carotid fork. There is enlargement of the artery or ulceration in the area after the stenosis in this close-up film. Note the narrowed segment toward the bottom of the picture.
Carotid stenosis - X-ray of the right artery
illustration
-
Stroke - illustration
A stroke involves loss of brain functions caused by a loss of blood circulation to areas of the brain. The blockage usually occurs when a clot or piece of atherosclerotic plaque breaks away from another area of the body and lodges within the vasculature of the brain.
Stroke
illustration
-
Brainstem function - illustration
A stroke affecting the brain stem is potentially life threatening since this area of the brain controls functions such as breathing and instructing the heart to beat. Brain stem stroke may also cause double vision, nausea and loss of coordination. The brain stem also controls less essential abilities such as articulate speech.
Brainstem function
illustration
-
Cerebellum - function - illustration
The cerebellum processes input from other areas of the brain, spinal cord and sensory receptors to provide precise timing for coordinated, smooth movements of the skeletal muscular system. A stroke affecting the cerebellum may cause dizziness, nausea, balance and coordination problems.
Cerebellum - function
illustration
-
Circle of Willis - illustration
The Circle of Willis is the joining area of several arteries at the bottom (inferior) side of the brain. At the Circle of Willis, the internal carotid arteries branch into smaller arteries that supply oxygenated blood to over 80% of the cerebrum.
Circle of Willis
illustration
-
Left cerebral hemisphere - function - illustration
The left cerebral hemisphere controls movement of the right side of the body. Depending on the severity, a stroke affecting the left cerebral hemisphere may result in functional loss or motor skill impairment of the right side of the body, and may also cause loss of speech.
Left cerebral hemisphere - function
illustration
-
Right cerebral hemisphere - function - illustration
The right cerebral hemisphere controls movement of the left side of the body. Depending on the severity, a stroke affecting the right cerebral hemisphere may result in functional loss or motor skill impairment of the left side of the body. In addition, there may be impairment of the normal attention to the left side of the body and its surroundings.
Right cerebral hemisphere - function
illustration
-
Endarterectomy - illustration
Endarterectomy is a surgical procedure removing plaque material from the lining of an artery.
Endarterectomy
illustration
-
Plaque buildup in arteries - illustration
A heart attack or stroke may occur when an area of plaque (atherosclerosis) ruptures and a clot forms over the location, blocking the flow of blood to the organ's tissues.
Plaque buildup in arteries
illustration
-
Stroke - Series
Presentation
-
Carotid dissection - illustration
Stroke is defined as a loss of brain function due to blocked blood circulation to the brain. Strokes may be caused by a narrowing, obstruction, or leak in the lining of the carotid. This leaking of blood into the artery wall (dissection) may cause a clot to form, reducing blood flow and raising the risk of a stroke. The leak may arise from an injury to the neck, which means stroke secondary to carotid dissection may occur in young people as well as older people.
Carotid dissection
illustration
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Stroke
(Alt. Medicine)
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Stroke - InDepth
(In-Depth)
Review Date: 4/29/2023
Reviewed By: Joseph V. Campellone, MD, Department of Neurology, Cooper Medical School of Rowan University, Camden, NJ. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.