Alcoholic neuropathy
Neuropathy - alcoholic; Alcoholic polyneuropathyAlcoholic neuropathy is damage to the nerves that results from excessive drinking of alcohol.
Causes
The exact cause of alcoholic neuropathy is unknown. It likely includes both a direct poisoning of the nerve by the alcohol and the effect of poor nutrition associated with alcoholism. Up to half of long-term heavy alcohol users develop this condition.
In severe cases, nerves that regulate internal body functions (autonomic nerves) may be involved.
Symptoms
Symptoms of this condition include any of the following:
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Numbness in the arms and legs
Numbness
Numbness and tingling are abnormal sensations that can occur anywhere in your body, but they are often felt in your fingers, hands, feet, arms, or le...
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Abnormal sensations, such as "pins and needles"
Abnormal sensations
Numbness and tingling are abnormal sensations that can occur anywhere in your body, but they are often felt in your fingers, hands, feet, arms, or le...
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- Muscle problems, including weakness, cramps, aches, or spasms
Cramps
Muscle cramps are when a muscle gets tight (contracts) without you trying to tighten it, and it does not relax. Cramps may involve all or part of on...
Read Article Now Book Mark ArticleAches
Muscle aches and pains are common and can involve more than one muscle. Muscle pain also can involve ligaments, tendons, and fascia. Fascias are th...
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Heat intolerance, especially after exercise
Heat intolerance
Heat intolerance is a feeling of being overheated when the temperature around you rises. It can often cause heavy sweating. Heat intolerance usually...
Read Article Now Book Mark Article - Erection problems (impotence)
Impotence
An erection problem occurs when a man cannot get or keep an erection that is firm enough for intercourse. You may not be able to get an erection at ...
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Problems urinating, incontinence (leaking urine), feeling of incomplete bladder emptying, difficulty beginning to urinate
Problems urinating
Difficulty starting or maintaining a urine stream is called urinary hesitancy.
Read Article Now Book Mark ArticleIncontinence
Urinary (or bladder) incontinence occurs when you are not able to keep urine from leaking out of your urethra. The urethra is the tube that carries ...
Read Article Now Book Mark ArticleDifficulty beginning to urinate
Difficulty starting or maintaining a urine stream is called urinary hesitancy.
Read Article Now Book Mark Article - Constipation or diarrhea
- Nausea, vomiting
- Problems swallowing or talking
- Unsteady gait (walking)
Changes in muscle strength or sensation usually occur on both sides of the body and are more common in the legs than in the arms. Symptoms usually develop gradually and become worse over time.
Exams and Tests
Your health care provider will perform a physical exam and ask about symptoms. An eye exam may show eye problems.
Excessive alcohol use often makes the body unable to use or store certain vitamins and minerals. Blood tests will be ordered to check for a deficiency (lack) of:
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Thiamine (vitamin B1)
Thiamine
Thiamin is one of the B vitamins. The B vitamins are a group of water-soluble vitamins that are part of many of the chemical reactions in the body....
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Pyridoxine (vitamin B6)
Pyridoxine
Vitamin B6 is a water-soluble vitamin. Water-soluble vitamins dissolve in water so the body cannot store them. Leftover amounts of the vitamin leav...
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Vitamin B12
Vitamin B12
Vitamin B12 is a water-soluble vitamin. Water-soluble vitamins dissolve in water. After the body uses what it needs of these vitamins, leftover amo...
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Folic acid
Folic acid
Folic acid and folate are both terms for a type of B vitamin (vitamin B9). Folate is a B vitamin that occurs naturally in foods such as green leafy v...
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Other tests may be ordered to check for other possible causes of neuropathy or damage to body systems due to neuropathy. Tests may include:
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Electrolyte levels, including glucose to check for diabetes
Electrolyte levels
Electrolytes are minerals in your blood and other body fluids that carry an electric charge. Electrolytes affect how your body functions in many ways...
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Electromyography (EMG) to check the health of the muscles and the nerves that control the muscles
Electromyography
Electromyography (EMG) is a test that checks the health of the muscles and the nerves that control the muscles.
Read Article Now Book Mark Article - Hemoglobin A1c test to check for diabetes
- Liver and kidney function tests
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Thyroid function tests
Thyroid function tests
Thyroid function tests are used to check whether your thyroid is working normally. The most common thyroid function tests are:Free T4 (free thyroxine...
Read Article Now Book Mark Article - Levels of vitamins and minerals in the body
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Nerve conduction tests to check how fast electrical signals move through a nerve
Nerve conduction tests
Nerve conduction velocity (NCV) is a test to see how fast electrical signals move through a nerve. This test is done along with electromyography (EM...
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Nerve biopsy to remove a small piece of a nerve for examination
Nerve biopsy
A nerve biopsy is the removal of a small piece of a nerve for examination.
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Upper GI and small bowel series
Upper GI and small bowel series
An upper GI and small bowel series is a set of x-rays taken to examine the esophagus, stomach, and small intestine. Barium enema is a related test th...
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Esophagogastroduodenoscopy (EGD) to examine the lining of the esophagus, stomach, and first part of the small intestine
Esophagogastroduodenoscopy
Esophagogastroduodenoscopy (EGD) is a test to examine the lining of the esophagus, stomach, and first part of the small intestine (the duodenum)....
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Voiding cystourethrogram, an x-ray study of the bladder and urethra
Voiding cystourethrogram
A voiding cystourethrogram is an x-ray study of the bladder and urethra. It is done while the bladder is emptying.
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Treatment
Stopping the use of alcohol is the most important first step. People will often need counseling from alcohol use disorder specialists. If there are other medical problems that can also cause nerve damage, such as diabetes, they should be treated as well. Once the alcohol problem has been addressed, treatment goals include:
- Controlling symptoms
- Maximizing ability to function independently
- Preventing injury
It is important to supplement the diet with vitamins, including thiamine and folic acid.
Physical therapy and orthopedic appliances (such as splints) may be needed to maintain muscle function and limb position.
Medicines may be needed to treat pain or uncomfortable sensations due to nerve damage. They will be prescribed the smallest dose of medicine needed to reduce symptoms. This may help prevent drug dependence and other side effects of chronic use.
Chronic
Chronic refers to something that continues over an extended period of time. A chronic condition is usually long-lasting and does not easily or quick...
Read Article Now Book Mark ArticlePositioning or the use of a bed frame that keeps the covers off the legs may help reduce pain.
People with lightheadedness or dizziness when standing up (orthostatic hypotension) may need to try several different treatments before finding one that successfully reduces their symptoms. Treatments that may help include:
- Wearing compression stockings
Compression stockings
You wear compression stockings to improve blood flow in the veins of your legs. Compression stockings gently squeeze your legs to move blood up your...
Read Article Now Book Mark Article - Eating extra salt
- Sleeping with the head elevated
- Using medicines
Bladder problems may be treated with:
- Manual expression of urine
- Intermittent catheterization (male or female)
Male
A urinary catheter tube drains urine from your bladder. You may need a catheter because you have urinary incontinence (leakage), urinary retention (...
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You will use a catheter (tube) to drain urine from your bladder. You may need a catheter because you have urinary incontinence (leakage), urinary re...
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Impotence, diarrhea, constipation, or other symptoms are treated when necessary. These symptoms often respond poorly to treatment in people with alcoholic neuropathy.
It is important to protect body parts with reduced sensation from injury. This may include:
- Checking the temperature of bath water to prevent burns
- Changing footwear
- Frequently inspecting the feet and shoes to reduce injury caused by pressure or objects in the shoes
- Guarding the extremities to prevent injury from pressure
Alcohol must be stopped to prevent the damage from getting worse. Treatment for alcoholism may include counseling, social support such as Alcoholics Anonymous (AA), or medicines.
Outlook (Prognosis)
Damage to nerves from alcoholic neuropathy is usually permanent. It is likely to get worse if the person continues to use alcohol or if nutritional problems are not corrected. Alcoholic neuropathy is usually not life threatening, but it can severely affect quality of life.
When to Contact a Medical Professional
Call for an appointment with your provider if you have symptoms of alcoholic neuropathy.
Prevention
The only way to prevent alcoholic neuropathy is not to drink excessive amounts of alcohol.
References
Katirji B. Disorders of peripheral nerves. In: Jankovic J, Mazziotta JC, Pomeroy SL, Newman NJ, eds. Bradley's and Daroff's Neurology in Clinical Practice. 8th ed. Philadelphia, PA: Elsevier; 2022:chap 106.
Koppel BS. Nutritional and alcohol-related neurologic disorders. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 388.
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Alcoholic neuropathy - illustration
Alcoholic neuropathy is damage to the nerves that results from excessive drinking of alcohol. The damage may affect the autonomic nerves (those that regulate internal body functions) and the nerves that control movement and sensation.
Alcoholic neuropathy
illustration
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Motor nerves - illustration
Motor nerves are the nerves responsible for all voluntary skeletal and somatic movement such as moving the leg or arm.
Motor nerves
illustration
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Autonomic Nerves - illustration
Autonomic nerves are concerned with muscular functions which are reflexive, such as breathing, heartbeats and peristalsis (rhythmic movements of the intestines).
Autonomic Nerves
illustration
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Central nervous system and peripheral nervous system - illustration
The central nervous system comprises the brain and spinal cord. The peripheral nervous system includes nerves outside the brain and spinal cord.
Central nervous system and peripheral nervous system
illustration
-
Alcoholic neuropathy - illustration
Alcoholic neuropathy is damage to the nerves that results from excessive drinking of alcohol. The damage may affect the autonomic nerves (those that regulate internal body functions) and the nerves that control movement and sensation.
Alcoholic neuropathy
illustration
-
Motor nerves - illustration
Motor nerves are the nerves responsible for all voluntary skeletal and somatic movement such as moving the leg or arm.
Motor nerves
illustration
-
Autonomic Nerves - illustration
Autonomic nerves are concerned with muscular functions which are reflexive, such as breathing, heartbeats and peristalsis (rhythmic movements of the intestines).
Autonomic Nerves
illustration
-
Central nervous system and peripheral nervous system - illustration
The central nervous system comprises the brain and spinal cord. The peripheral nervous system includes nerves outside the brain and spinal cord.
Central nervous system and peripheral nervous system
illustration
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Betaine
(Alt. Medicine)
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Vitamins and Phytonutrients - InDepth
(In-Depth)
Review Date: 4/29/2023
Reviewed By: Joseph V. Campellone, MD, Department of Neurology, Cooper Medical School of Rowan University, Camden, NJ. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.