Lung metastases
Lung metastases are cancerous tumors that start somewhere else in the body and spread to the lungs.
Causes
Metastatic tumors in the lungs are cancers that developed at other places in the body (or other parts of the lungs). They then spread through the bloodstream or lymphatic system to the lungs. It is different than lung cancer that starts in the lungs.
Lung cancer - Animation
Cancer can affect just about any part of the body, from the colon to the pancreas. Some cancers grow quickly, while others grow more slowly and are easier to treat. But of all the different cancers out there, one of the deadliest is lung cancer. Let's talk today about lung cancer. Cancer starts when cells begin to grow uncontrollably and form tumors. In the case of lung cancer, the tumors start in the lungs. Sometimes cancer starts somewhere else in the body and then spreads to the lungs. In that case, it's called metastatic cancer to the lung. Metastatic means disease that has spread. There are two types of lung cancer. The most common, and slower-growing form is non-small cell lung cancer. The other, faster-growing form is called small cell lung cancer. The most common way to get lung cancer is to smoke cigarettes. The more cigarettes you smoke and the earlier you start smoking, the greater your risk is. Even being around someone who smokes and breathing in the secondhand smoke from their cigarettes increases your risk of getting lung cancer. Even though smoking makes you much more likely to get lung cancer, you don't have to smoke or be exposed to smoke to get the disease. Some people who have lung cancer never lit up a cigarette in their life. They have been exposed to cancer-causing substances like asbestos, diesel fumes, arsenic, radiation, or radon gas. Or, they may not have had any known lung cancer risks. The most common signs of lung cancer are a cough that won't go away, chest pain, shortness of breath, weight loss, and fatigue. But just because you have these symptoms it doesn't mean that you have don't have lung cancer. These can also be signs of other conditions, like asthma or a respiratory infection. If you do have these symptoms, see your doctor. A chest x-ray, MRI, or CT scan can view the inside of your lungs to look for signs of cancer or other diseases. What happens if you do have lung cancer? Doctors divide lung cancer into stages. The higher the stage, the more the cancer has spread. For example, a stage 1 cancer is small and hasn't spread outside of the lungs. A stage 4 cancer has spread to the other organs, such as the kidneys or brain. Depending upon the type and stage of your lung cancer, you may need surgery to remove part or all of your lung. Or, your doctor may recommend radiation or chemotherapy to kill cancer cells. If you have lung cancer, how well you do depends upon the stage of your disease and the type of lung cancer that you have. Early-stage cancers have the highest survival and cure rates. Late-stage cancers are harder to treat. Because lung cancer can be so deadly, prevention is key. The most important that thing you can do is to stop smoking, and avoid being around anyone who does smoke.
Nearly any cancer can spread to the lungs. Common cancers include:
- Bladder cancer
Bladder cancer
Bladder cancer is a cancer that starts in the bladder. The bladder is the body part that holds and releases urine. It is in the center of the lower...
Read Article Now Book Mark Article - Breast cancer
Breast cancer
Breast cancer is cancer that starts in the tissues of the breast. There are two main types of breast cancer:Ductal carcinoma starts in the tubes (du...
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- Colorectal cancer
Colorectal cancer
Colorectal cancer is cancer that starts in the large intestine (colon) or the rectum (end of the colon). It is also sometimes simply called colon ca...
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- Melanoma
Melanoma
Melanoma is the most dangerous type of skin cancer. It is also the rarest. It is the leading cause of death from skin disease. Other common types o...
Read Article Now Book Mark Article - Ovarian cancer
Ovarian cancer
Ovarian cancer is cancer that starts in the ovaries. The ovaries are the female reproductive organs that produce eggs.
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- Thyroid cancer
Thyroid cancer
Thyroid cancer is a cancer that starts in the thyroid gland. The thyroid gland is located in the front of your lower neck.
Read Article Now Book Mark Article - Pancreatic cancer
Pancreatic cancer
Pancreatic cancer is cancer that starts in the pancreas.
Read Article Now Book Mark Article - Testicular cancer
Testicular cancer
Testicular cancer is cancer that starts in the testicles. The testicles are the male reproductive glands located in the scrotum.
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Symptoms
Symptoms may include any of the following:
- Bloody sputum
Bloody sputum
Coughing up blood is the spitting up of blood or bloody mucus from the lungs and throat (respiratory tract). Hemoptysis is the medical term for cough...
Read Article Now Book Mark Article - Chest pain
Chest pain
Chest pain is discomfort or pain that you feel anywhere along the front of your body between your neck and upper abdomen.
Read Article Now Book Mark Article - Cough
Cough
Coughing is an important way to keep your throat and airways clear. But too much coughing may mean you have a disease or disorder. Some coughs are d...
Read Article Now Book Mark Article - Shortness of breath
Shortness of breath
Breathing difficulty may involve:Difficult breathing Uncomfortable breathingFeeling like you are not getting enough air
Read Article Now Book Mark Article - Weakness
- Weight loss
Exams and Tests
Your health care provider will examine you and ask about your medical history and symptoms. Tests that may be done include:
- Bronchoscopy to view the airways and take tissue samples, if possible
Bronchoscopy
Bronchoscopy is a test to view the airways and diagnose lung disease. It may also be used during the treatment of some lung conditions.
Read Article Now Book Mark Article - Chest CT scan
Chest CT scan
A chest CT (computed tomography) scan is an imaging method that uses x-rays to create cross-sectional pictures of the chest and upper abdomen....
Read Article Now Book Mark Article - Chest x-ray
Chest x-ray
A chest x-ray is an x-ray of the chest, lungs, heart, large arteries, ribs, and diaphragm.
Read Article Now Book Mark Article - Cytologic studies of pleural fluid or sputum
Cytologic studies of pleural fluid
A cytology exam of pleural fluid is a laboratory test to detect cancer cells and certain other cells in the fluid from the area that surrounds the lu...
Read Article Now Book Mark Article - Lung needle biopsy
Lung needle biopsy
A lung needle biopsy is a method to remove a piece of lung tissue for examination. If it is done through the wall of your chest, it is called a tran...
Read Article Now Book Mark Article - PET scan
PET scan
A lung positron emission tomography (PET) scan is an imaging test. It uses a radioactive substance (called a tracer) to look for disease in the lung...
Read Article Now Book Mark Article - Surgery to take a sample of tissue from the lungs (surgical lung biopsy)
Surgical lung biopsy
An open lung biopsy is surgery to remove a small piece of tissue from the lung. The sample is then examined for cancer, infection, or lung disease....
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Treatment
Chemotherapy is often used to treat metastatic cancer to the lung. Surgery to remove the tumors may be done when any of the following occurs:
- The cancer has spread to only limited areas of the lung
- The lung tumors can be completely removed with surgery
However, the main tumor must be curable, and the person must be strong enough to go through the surgery and recovery.
Other treatments include:
- Radiation therapy
Radiation therapy
Radiation therapy uses high-powered radiation (such as x-rays or gamma rays), particles, or radioactive seeds to kill cancer cells.
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- Targeted systemic therapy
- The placement of stents inside the airways
Stents
A stent is a tiny tube placed into a hollow structure in your body. This structure can be an artery, a vein, or another structure, such as the tube ...
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Laser therapy
Laser therapy uses a very narrow, focused beam of light to shrink or destroy cancer cells. It can be used to cut out tumors without damaging other t...
Read Article Now Book Mark Article - Using local heat probes to destroy the cancer
- Using very cold temperature to destroy the cancer
Support Groups
You can ease the stress of illness by joining a support group where members share common experiences and problems.
Support group
The following organizations are good resources for information on cancer:American Cancer Society. Support and online communities. www. cancer. org/...
Read Article Now Book Mark ArticleOutlook (Prognosis)
A cure is unlikely in most cases of cancers that have spread to the lungs. But the outlook depends on the main cancer. In some cases, a person can live more than 5 years with metastatic cancer to the lungs.
Possible Complications
Complications of metastatic tumors in the lungs may include:
- Fluid between the lung and chest wall (pleural effusion), which can cause shortness of breath or pain when taking a deep breath
Pleural effusion
A pleural effusion is a buildup of fluid between the layers of tissue that line the lungs and chest cavity.
Read Article Now Book Mark Article - Further spread of the cancer
When to Contact a Medical Professional
Contact your provider if you have a history of cancer and you develop:
- Coughing up blood
- Persistent cough
- Shortness of breath
- Unexplained weight loss
Prevention
Not all cancers can be prevented. However, many can be prevented by:
- Eating healthy foods
- Exercising regularly
- Limiting alcohol consumption
- Not smoking
Reviewed By
Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
Arenberg DA, Reddy RM. Metastatic malignant tumors. In: Broaddus VC, Ernst JD, King TE, et al, eds. Murray and Nadel's Textbook of Respiratory Medicine. 7th ed. Philadelphia, PA: Elsevier; 2022:chap 79.
Hayman J, Naidoo J, Ettinger DS. Lung metastases. In: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6th ed. Philadelphia, PA: Elsevier; 2020:chap 57.
Wald O, Izhar U, Sugarbaker DJ. Lung, chest wall, pleura, and mediastinum. In: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. Sabiston Textbook of Surgery. 21st ed. St Louis, MO: Elsevier; 2022:chap 58.