Cancer treatment - early menopause
Premature menopause; Ovarian insufficiency - cancerCertain types of cancer treatments can cause women to have early menopause. This is menopause that occurs before age 40. It happens when your ovaries stop working and you no longer have periods and cannot get pregnant.
Menopause
Menopause is the time in a woman's life when her periods (menstruation) stop. Most often, it is a natural, normal body change that occurs between ag...
Read Article Now Book Mark ArticleEarly menopause can cause symptoms such as hot flashes and vaginal dryness. Your health care provider can help you find treatments for these symptoms.
Hot flashes
Certain types of cancer treatments can cause hot flashes and night sweats. Hot flashes are when your body suddenly feels hot. In some cases, hot fl...
Read Article Now Book Mark ArticleTreatments That can Cause Early Menopause
Cancer treatments that can cause early menopause include:
- Surgery. Having both ovaries removed causes menopause to happen right away. If you are age 50 or younger, your provider may try to leave an ovary or part of an ovary if possible. This can keep you from having early menopause.
- Chemotherapy (chemo). Some types of chemo can damage your ovaries and cause early menopause. You may have menopause right away or months after treatment. Your risk of early menopause from chemo depends on the type and amount of chemo drug you have. The younger you are, the less likely you will have early menopause from chemo.
Chemotherapy (chemo)
The term chemotherapy is used to describe cancer-killing drugs. Chemotherapy may be used to:Cure the cancerShrink the cancerPrevent the cancer from ...
Read Article Now Book Mark Article - Radiation. Getting radiation in your pelvic area can also damage your ovaries. In some cases, your ovaries may heal and start working again. But, if you get large doses of radiation, the damage may be permanent.
Radiation
Radiation therapy uses high-powered radiation (such as x-rays or gamma rays), particles, or radioactive seeds to kill cancer cells.
Read Article Now Book Mark Article - Hormone therapy. These treatments used to treat breast and uterine cancers can often cause early menopause.
Hormone therapy
Hormone therapy to treat breast cancer uses drugs or treatments to lower levels or block the action of female sex hormones (estrogen and progesterone...
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Ask your provider if your cancer treatment may cause early menopause.
Effects of Early Menopause
When your ovaries are removed or stop working, they no longer make estrogen. This causes the same symptoms as natural menopause.
- Vaginal dryness or tightness
- Hot flashes
- Mood changes
- Lower sex drive
- Problems sleeping
In some cases, these symptoms may come on strong and can be severe.
Less estrogen in your body also increases your risk for certain health conditions, such as:
- Heart disease
Heart disease
People often do not consider heart disease a woman's disease. Yet cardiovascular disease is the leading killer of women over age 25. It kills nearl...
Read Article Now Book Mark Article - Osteoporosis (thinning of bones)
Osteoporosis
Osteoporosis is a disease in which bones become fragile and more likely to break (fracture).
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How to Ease Symptoms
Many treatments can help ease the symptoms of early menopause. They include medicines and lifestyle treatments you can do at home.
Some medicines that may help include:
- Hormone therapy. In some cases, your provider may prescribe female hormones to help with hot flashes and other symptoms. But, there are some risks with hormones, and you may not be able to take them if you have had certain types of cancer.
Hormone therapy
Hormone therapy (HT) uses one or more hormones to treat symptoms of menopause. HT uses estrogen, progestin (a type of progesterone), or both. Somet...
Read Article Now Book Mark Article - Vaginal estrogen. Even if you cannot take hormone therapy by mouth or skin patch, you may be able to use small amounts of estrogen in or around your vagina to help with dryness. These hormones come in creams, gels, tablets, and rings. You need a prescription from your provider for these medicines.
- Other medicines. If you cannot take hormones, your provider may prescribe another type of medicine to help with hot flashes, such as certain antidepressants (even if you are not depressed) or other medicines. Because of their chemical effects, these are effective for hot flashes even if you are not depressed.
- Lubricants or moisturizers. These products can help make sex more comfortable if you have vaginal dryness. Look for a water-based lubricant, such as K-Y Jelly or Astroglide. Or, try using a vaginal moisturizer like Replens every few days.
- Medicines for bone loss. Some women take medicines to help reduce bone loss after menopause. Ask your provider if this type of medicine may be right for you.
Treatments you can try at home include:
- Staying active. Getting regular exercise can help with mood swings, sleep problems, and mild hot flashes.
- Healthy sleep habits. Getting enough sleep may help ease mood swings. But, if you are having trouble sleeping at night, try skipping naps during the day. You should also avoid caffeine late in the day, and do not have large meals or do anything too active right before bedtime.
- Dressing in layers. This can help with hot flashes, since you can remove layers when you feel hot. It can also help to dress in loose, cotton clothing.
Ask your provider what treatments might work best for you.
Protecting Your Bones and Heart
Since early menopause can affect your bone and heart health, it's important to take steps to keep them healthy. Here is how:
- Eat healthy foods. Focus on fresh fruits and vegetables, whole grains, lean meats, fish, nuts, beans, and low-fat dairy products.
- Get enough calcium and vitamin D. These nutrients help build bones. Foods rich in calcium include fat-free yogurt and milk, spinach, and white beans. Your body makes most of its vitamin D from the sun, but you can also get it from salmon, eggs, and milk that has vitamin D added. Ask your provider if you need to take supplements.
- Get exercise. The best kinds of exercise for your bones are weight-bearing exercises that work your body against gravity. Some ideas include walking, yoga, hiking, dancing, lifting weights, gardening, and tennis.
- DO NOT smoke. Smoking raises your risk for both osteoporosis and heart disease. If you need help quitting, ask your provider.
- Ask about a bone density test. This is a test that checks for osteoporosis. This is a recommended test for all women at age 65, but you should consider one earlier if you have early menopause.
Ask about a bone density test
A bone mineral density (BMD) test measures how much calcium and other types of minerals are in an area of your bone. This test helps your health care...
Read Article Now Book Mark Article - Keep track of your numbers. Make sure your provider checks your blood pressure, cholesterol, and blood sugar levels regularly. These simple tests can help tell you if you are at risk for heart disease or stroke.
References
Mitsis D, Beaupin LK, O'Connor T. Reproductive complications. In: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6th ed. Philadelphia, PA: Elsevier; 2020:chap 43.
National Cancer Institute website. Sexual health issues in women with cancer. www.cancer.gov/about-cancer/treatment/side-effects/sexuality-women. Updated December 29, 2022. Accessed January 17, 2023.
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Review Date: 10/25/2022
Reviewed By: Frank D. Brodkey, MD, FCCM, Associate Professor, Section of Pulmonary and Critical Care Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.