Bone scan
Scintigraphy - boneA bone scan is an imaging test used to diagnose bone diseases and find out how severe they are.
How the Test is Performed
A bone scan involves injecting a very small amount of radioactive material (radiotracer) into a vein. This substance travels through your blood to your bones and organs. As it wears off, it gives off a bit of radiation. This radiation is detected by a camera that slowly scans your body. The camera takes pictures of how much radiotracer collects in your bones.
If a bone scan is done to see if you have a bone infection, images may be taken shortly after the radioactive material is injected and again 3 to 4 hours later, when it has collected in your bones. This process is called a 3-phase bone scan.
To evaluate whether cancer has spread to the bone (metastatic bone disease), images are taken only after the 3- to 4-hour delay.
Metastatic
Metastasis is the movement or spreading of cancer cells from one organ or tissue to another. Cancer cells usually spread through the blood or the ly...
Read Article Now Book Mark ArticleThe scanning part of the test will last about 1 hour. The scanner's camera may move above and around you. You may need to change positions.
You will probably be asked to drink extra water after you receive the radiotracer to help flush the material from your bladder.
How to Prepare for the Test
You must remove jewelry and other metal objects. You may be asked to wear a hospital gown.
Tell your health care provider if you are or may be pregnant.
Do not take any medicine with bismuth in it, such as Pepto-Bismol, for 4 days before the test.
Follow any other instructions you are given.
How the Test will Feel
There is a small amount of pain when the needle is inserted. During the scan, there is no pain. You must remain still during the scan. The technologist will tell you when to change positions.
You may experience some discomfort due to lying still for a long period.
Why the Test is Performed
A bone scan can be used to:
- Diagnose a bone tumor or cancer.
- Determine if a cancer that began elsewhere in your body has spread to your bones. Common cancers that spread to the bones include breast, lung, prostate, thyroid, and kidney.
- Diagnose a fracture, when it cannot be seen on a regular x-ray (most commonly hip fractures, stress fractures in the feet or legs, or spine fractures).
- Diagnose a bone infection (osteomyelitis).
Bone infection (osteomyelitis)
Osteomyelitis is a bone infection. It is caused by bacteria or other germs.
Read Article Now Book Mark Article - Diagnose or determine the cause of bone pain, when no other cause has been identified.
- Evaluate metabolic disorders, such as osteomalacia, primary hyperparathyroidism, osteoporosis, complex regional pain syndrome, and Paget disease.
Osteomalacia
Osteomalacia is softening of the bones. It most often occurs because of a problem that leads to vitamin D deficiency, which helps your body absorb c...
Read Article Now Book Mark ArticlePrimary hyperparathyroidism
Hyperparathyroidism is a condition in which 1 or more of the parathyroid glands in your neck produce too much parathyroid hormone (PTH).
Read Article Now Book Mark ArticleOsteoporosis
Osteoporosis is a disease in which bones become fragile and more likely to break (fracture).
Read Article Now Book Mark ArticleComplex regional pain syndrome
Complex regional pain syndrome (CRPS) is a long-term (chronic) pain condition that can affect any area of the body, but often affects an arm or a leg...
Read Article Now Book Mark ArticlePaget disease
Paget disease is a disorder that involves abnormal bone destruction and regrowth. This results in deformity of the affected bones.
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Normal Results
Test results are considered normal if the radiotracer is present evenly throughout all the bones.
What Abnormal Results Mean
An abnormal scan will show hot spots or cold spots as compared to surrounding bone. Hot spots are areas where there is an increased collection of the radioactive material. Cold spots are areas that have taken up less of the radioactive material.
Bone scan findings must be compared with other imaging studies, such as x-rays or CT scans, in addition to clinical information. Your provider will discuss any abnormal findings with you.
Risks
If you are pregnant or nursing, the test may be postponed to prevent exposing your baby to radiation. If you must have the test while breastfeeding, you should pump and throw away the breast milk for the next 2 days.
The amount of radiation injected into your vein is very small. All radiation is gone from your body within 2 to 3 days. The radiotracer that is used exposes you to a very small amount of radiation. The risk is probably no greater than with routine x-rays.
Risks related to the bone radiotracer are rare, but may include:
- Anaphylaxis (severe allergic response)
Anaphylaxis
Anaphylaxis is a life-threatening type of allergic reaction.
Read Article Now Book Mark Article - Rash
Rash
Rashes involve changes in the color, feeling or texture of your skin.
Read Article Now Book Mark Article - Swelling
Swelling
Swelling is the enlargement of organs, skin, or other body parts. It is caused by a buildup of fluid in the tissues. The extra fluid can lead to a ...
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There is a slight risk of infection or bleeding when the needle is inserted into a vein.
References
Kapoor G, Toms AP. Current status of imaging of the musculoskeletal system. In: Adam A, Dixon AK, Gillard JH, Schaefer-Prokop CM, eds. Grainger & Allison's Diagnostic Radiology. 7th ed. Philadelphia, PA: Elsevier; 2021:chap 38.
Ribbens C, Namur G. Bone scintigraphy and positron emission tomography. In: Hochberg MC, Gravallese EM, Smolen JS, van der Heijde D, Weinblatt ME, Weisman MH, eds. Rheumatology. 8th ed. Philadelphia, PA: Elsevier; 2023:chap 47.
Nuclear scan - illustration
A radiotracer is injected into a peripheral vein. As the radiotracer decays, gamma radiation is emitted and is detected by a Gamma camera. When the tracer has collected in the target organ the area is scanned. Radionuclide scans can detect abnormalities such as fractures, bone infections, arthritis, rickets, and tumors that have spread, among other diseases.
Nuclear scan
illustration
Nuclear scan - illustration
A radiotracer is injected into a peripheral vein. As the radiotracer decays, gamma radiation is emitted and is detected by a Gamma camera. When the tracer has collected in the target organ the area is scanned. Radionuclide scans can detect abnormalities such as fractures, bone infections, arthritis, rickets, and tumors that have spread, among other diseases.
Nuclear scan
illustration
Review Date: 5/19/2023
Reviewed By: Jatin M. Vyas, MD, PhD, Associate Professor in Medicine, Harvard Medical School; Associate in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, MA. Internal review and update on 01/31/2024 by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.