BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menu5'-nucleotidase 5'-NT5'-nucleotidase (5'-NT) is a protein produced by the liver. A test can be done to measure the amount of this protein in your blood. How the Test is Performed Blood is drawn from a vein. You may feel slight pain or a sting when the needle is inserted. Afterward, there may be some throbbing.Blood is drawn from a veinVenipuncture is the collection of blood from a vein. It is most often done for laboratory testing.ImageRead Article Now Book Mark Article How to Prepare for the Test Your health care provider may tell you to stop taking some medicines that could interfere with the test. Drugs that may affect results include:Acetaminophen (Tylenol) Halothane Isoniazid Methyldopa Nitrofurantoin Why the Test is Performed Your provider may order this test if you have signs of a liver problem. It is used mostly to tell if the high protein level is due to liver damage or skeletal muscle damage. Normal Results The normal value is 2 to 17 units per liter.Normal value ranges may vary slightly among different laboratories. Talk to your provider about the meaning of your specific test results.The examples above show the common measurements for results for these tests. Some laboratories use different measurements or may test different specimens. What Abnormal Results Mean Greater than normal levels may indicate:Cirrhosis (scarring of the liver and poor liver function) Flow of bile from the liver is blocked (cholestasis) Heart failure Hepatitis (inflamed liver) Liver cancer or tumor Liver ischemia (reduced blood flow to the liver) Liver necrosis (death of liver tissue) Lung disease Ovarian cancer Ovarian cancerOvarian cancer is cancer that starts in the ovaries. The ovaries are the female reproductive organs that produce eggs.ImageRead Article Now Book Mark Article Pancreas disease Rheumatoid arthritis Rheumatoid arthritisRheumatoid arthritis (RA) is a disease that leads to inflammation of the joints and surrounding tissues. It is a long-term disease. It can also aff...ImageRead Article Now Book Mark Article Use of medicines that are toxic to the liver Risks Slight risks from having blood drawn may include:Excessive bleeding Fainting or feeling lightheaded Hematoma (blood accumulating under the skin) Infection (a slight risk any time the skin is broken) Bruising Open ReferencesReferencesPincus MR, Carty RP. Clinical enzymology. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Philadelphia, PA: Elsevier; 2022:chap 21.Pratt DS. Liver chemistry and function tests. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 11th ed. Philadelphia, PA: Elsevier; 2021:chap 73.AllVideoImagesTogBlood test - illustration Blood is drawn from a vein (venipuncture), usually from the inside of the elbow or the back of the hand. A needle is inserted into the vein, and the blood is collected in an air-tight vial or a syringe. Preparation may vary depending on the specific test.Blood testillustrationBlood test - illustration Blood is drawn from a vein (venipuncture), usually from the inside of the elbow or the back of the hand. A needle is inserted into the vein, and the blood is collected in an air-tight vial or a syringe. Preparation may vary depending on the specific test.Blood testillustration Tests for 5'-nucleotidase 5'-nucleotidase Related Information ALP - blood test(Medical Test)Aspartate aminotransferase (AST) blood test(Medical Test)Alanine transaminase (ALT) blood test(Medical Test)Enzyme(Special Topic)Cholestasis(Condition)Biliary system(Special Topic)Gallstones(Condition)Hepatic ischemia(Condition)Necrosis(Special Topic)Liver cancer - hepatocellular carcinoma(Condition)Gallstones and gallbladder disease - InDepth(In-Depth)Hepatitis - InDepth(In-Depth) Review Date: 2/28/2023 Reviewed By: Jacob Berman, MD, MPH, Clinical Assistant Professor of Medicine, Division of General Internal Medicine, University of Washington School of Medicine, Seattle, WA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. 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5'-nucleotidase 5'-NT5'-nucleotidase (5'-NT) is a protein produced by the liver. A test can be done to measure the amount of this protein in your blood. How the Test is Performed Blood is drawn from a vein. You may feel slight pain or a sting when the needle is inserted. Afterward, there may be some throbbing.Blood is drawn from a veinVenipuncture is the collection of blood from a vein. It is most often done for laboratory testing.ImageRead Article Now Book Mark Article How to Prepare for the Test Your health care provider may tell you to stop taking some medicines that could interfere with the test. Drugs that may affect results include:Acetaminophen (Tylenol) Halothane Isoniazid Methyldopa Nitrofurantoin Why the Test is Performed Your provider may order this test if you have signs of a liver problem. It is used mostly to tell if the high protein level is due to liver damage or skeletal muscle damage. Normal Results The normal value is 2 to 17 units per liter.Normal value ranges may vary slightly among different laboratories. Talk to your provider about the meaning of your specific test results.The examples above show the common measurements for results for these tests. Some laboratories use different measurements or may test different specimens. What Abnormal Results Mean Greater than normal levels may indicate:Cirrhosis (scarring of the liver and poor liver function) Flow of bile from the liver is blocked (cholestasis) Heart failure Hepatitis (inflamed liver) Liver cancer or tumor Liver ischemia (reduced blood flow to the liver) Liver necrosis (death of liver tissue) Lung disease Ovarian cancer Ovarian cancerOvarian cancer is cancer that starts in the ovaries. The ovaries are the female reproductive organs that produce eggs.ImageRead Article Now Book Mark Article Pancreas disease Rheumatoid arthritis Rheumatoid arthritisRheumatoid arthritis (RA) is a disease that leads to inflammation of the joints and surrounding tissues. It is a long-term disease. It can also aff...ImageRead Article Now Book Mark Article Use of medicines that are toxic to the liver Risks Slight risks from having blood drawn may include:Excessive bleeding Fainting or feeling lightheaded Hematoma (blood accumulating under the skin) Infection (a slight risk any time the skin is broken) Bruising Open ReferencesReferencesPincus MR, Carty RP. Clinical enzymology. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Philadelphia, PA: Elsevier; 2022:chap 21.Pratt DS. Liver chemistry and function tests. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 11th ed. Philadelphia, PA: Elsevier; 2021:chap 73.