BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuTrypsinogen testSerum trypsin; Trypsin-like immunoreactivity; Serum trypsinogen; Immunoreactive trypsinTrypsinogen is a substance that is normally produced in the pancreas and released into the small intestine. Trypsinogen is converted to trypsin. Then it starts the process needed to break down proteins into their building blocks (called amino acids).A test can be done to measure the amount of trypsinogen in your blood. How the Test is Performed A blood sample is taken from a vein. The blood sample is sent to a lab for testing.Blood sample is taken from a veinVenipuncture is the collection of blood from a vein. It is most often done for laboratory testing.ImageRead Article Now Book Mark Article How to Prepare for the Test There are no special preparations. You may be asked to not eat or drink for 8 hours before the test. How the Test will Feel You may feel slight pain or a sting when the needle is inserted to draw blood. Afterward, there may be some throbbing. Why the Test is Performed This test is done to detect diseases of the pancreas.The test is also used to screen newborn babies for cystic fibrosis.Cystic fibrosisCystic fibrosis is a disease that causes thick, sticky mucus to build up in the lungs, digestive tract, and other areas of the body. It is one of th...ImageRead Article Now Book Mark Article Normal Results Normal value ranges may vary slightly among different laboratories. Talk to your health care provider about the meaning of your specific test results. What Abnormal Results Mean Increased levels of trypsinogen may be due to:Abnormal production of pancreatic enzymes Acute pancreatitis Acute pancreatitisAcute pancreatitis is sudden swelling and inflammation of the pancreas.ImageRead Article Now Book Mark Article Cystic fibrosis Pancreatic cancerPancreatic cancerPancreatic cancer is cancer that starts in the pancreas.ImageRead Article Now Book Mark Article Very low levels may be seen in people with chronic pancreatitis.Chronic pancreatitisPancreatitis is swelling of the pancreas. Chronic pancreatitis is present when this problem does not heal or recurs and does not improve, gets worse...ImageRead Article Now Book Mark Article Risks There is little risk involved with having your blood taken. Veins and arteries vary in size from one person to another and from one side of the body to the other. Taking blood from some people may be more difficult than from others.Other risks associated with having blood drawn are slight, but may include:Fainting or feeling lightheaded Multiple punctures to locate veins Hematoma (blood buildup under the skin) Excessive bleeding Infection (a slight risk any time the skin is broken) Considerations Other tests used to detect pancreas diseases may include:Serum amylase Serum lipase Open ReferencesReferencesChernecky CC, Berger BJ. Trypsin- plasma or serum. In: Chernecky CC, Berger BJ, eds. Laboratory Tests and Diagnostic Procedures. 6th ed. St Louis, MO: Elsevier Saunders; 2013:1125-1126.Forsmark CE. Chronic pancreatitis. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 11th ed. Philadelphia, PA: Elsevier; 2021:chap 59.Siddiqi HA, Rabinowitz S, Axiotis CA. Laboratory diagnosis of gastrointestinal and pancreatic disorders. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Philadelphia, PA: Elsevier; 2022:chap 23.AllVideoImagesTogBlood test - illustration Blood is drawn from a vein (venipuncture), usually from the inside of the elbow or the back of the hand. A needle is inserted into the vein, and the blood is collected in an air-tight vial or a syringe. Preparation may vary depending on the specific test.Blood testillustrationBlood test - illustration Blood is drawn from a vein (venipuncture), usually from the inside of the elbow or the back of the hand. A needle is inserted into the vein, and the blood is collected in an air-tight vial or a syringe. Preparation may vary depending on the specific test.Blood testillustration Tests for Trypsinogen test Trypsinogen testNeonatal cystic fibrosis screening testRelated Information Enzyme(Special Topic)Protein in diet(Nutrition)Duodenum(Special Topic)Pancreatic cancer(Condition)Acute(Special Topic)Chronic pancreatitis(Condition) Review Date: 1/30/2023 Reviewed By: Michael M. Phillips, MD, Emeritus Professor of Medicine, The George Washington University School of Medicine, Washington, DC. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. 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Trypsinogen testSerum trypsin; Trypsin-like immunoreactivity; Serum trypsinogen; Immunoreactive trypsinTrypsinogen is a substance that is normally produced in the pancreas and released into the small intestine. Trypsinogen is converted to trypsin. Then it starts the process needed to break down proteins into their building blocks (called amino acids).A test can be done to measure the amount of trypsinogen in your blood. How the Test is Performed A blood sample is taken from a vein. The blood sample is sent to a lab for testing.Blood sample is taken from a veinVenipuncture is the collection of blood from a vein. It is most often done for laboratory testing.ImageRead Article Now Book Mark Article How to Prepare for the Test There are no special preparations. You may be asked to not eat or drink for 8 hours before the test. How the Test will Feel You may feel slight pain or a sting when the needle is inserted to draw blood. Afterward, there may be some throbbing. Why the Test is Performed This test is done to detect diseases of the pancreas.The test is also used to screen newborn babies for cystic fibrosis.Cystic fibrosisCystic fibrosis is a disease that causes thick, sticky mucus to build up in the lungs, digestive tract, and other areas of the body. It is one of th...ImageRead Article Now Book Mark Article Normal Results Normal value ranges may vary slightly among different laboratories. Talk to your health care provider about the meaning of your specific test results. What Abnormal Results Mean Increased levels of trypsinogen may be due to:Abnormal production of pancreatic enzymes Acute pancreatitis Acute pancreatitisAcute pancreatitis is sudden swelling and inflammation of the pancreas.ImageRead Article Now Book Mark Article Cystic fibrosis Pancreatic cancerPancreatic cancerPancreatic cancer is cancer that starts in the pancreas.ImageRead Article Now Book Mark Article Very low levels may be seen in people with chronic pancreatitis.Chronic pancreatitisPancreatitis is swelling of the pancreas. Chronic pancreatitis is present when this problem does not heal or recurs and does not improve, gets worse...ImageRead Article Now Book Mark Article Risks There is little risk involved with having your blood taken. Veins and arteries vary in size from one person to another and from one side of the body to the other. Taking blood from some people may be more difficult than from others.Other risks associated with having blood drawn are slight, but may include:Fainting or feeling lightheaded Multiple punctures to locate veins Hematoma (blood buildup under the skin) Excessive bleeding Infection (a slight risk any time the skin is broken) Considerations Other tests used to detect pancreas diseases may include:Serum amylase Serum lipase Open ReferencesReferencesChernecky CC, Berger BJ. Trypsin- plasma or serum. In: Chernecky CC, Berger BJ, eds. Laboratory Tests and Diagnostic Procedures. 6th ed. St Louis, MO: Elsevier Saunders; 2013:1125-1126.Forsmark CE. Chronic pancreatitis. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 11th ed. Philadelphia, PA: Elsevier; 2021:chap 59.Siddiqi HA, Rabinowitz S, Axiotis CA. Laboratory diagnosis of gastrointestinal and pancreatic disorders. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Philadelphia, PA: Elsevier; 2022:chap 23.