BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuAnti-DNase B blood testStrep throat - anti-DNase B test; Antideoxyribonuclease B titer; ADN-B testAnti-DNase B is a blood test to look for antibodies to a substance (protein) produced by group A streptococcus. This is the bacteria that cause strep throat.Strep throatStrep throat is a disease that causes a sore throat (pharyngitis). It is an infection with a bacteria called group A streptococcus.ImageRead Article Now Book Mark Article When used together with the ASO titer test, more than 90% of past streptococcal infections can be identified.ASO titer testAntistreptolysin O (ASO) titer is a blood test to measure antibodies against streptolysin O, a substance produced by group A streptococcus bacteria. ...ImageRead Article Now Book Mark Article How the Test is Performed A blood sample is needed.Blood sample is neededVenipuncture is the collection of blood from a vein. It is most often done for laboratory testing.ImageRead Article Now Book Mark Article How to Prepare for the Test No special preparation is necessary. How the Test will Feel When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging sensation. Afterward, there may be some throbbing or a slight bruise. This soon goes away. Why the Test is Performed This test is most often done to tell if you have previously had a strep infection and if you might have rheumatic fever or kidney problems (glomerulonephritis) due to that infection.Rheumatic feverRheumatic fever is a disease that may develop after an infection with group A streptococcus bacteria (such as strep throat or scarlet fever). It can...Read Article Now Book Mark Article GlomerulonephritisGlomerulonephritis is a type of kidney disease in which the part of your kidneys that helps filter waste and fluids from the blood is damaged....ImageRead Article Now Book Mark Article Normal Results A negative test is normal. Some people have low concentrations of antibodies, but they have not had a recent strep infection. Therefore, normal values in different age groups are:Adults: less than 85 units/milliliter (mL) School-age children: less than 170 units/mL Preschool children: less than 60 units/mLNormal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different specimens. Talk to your health care provider about the meaning of your specific test results. What Abnormal Results Mean Increased levels of DNase B levels indicate exposure to group A streptococcus. Risks There is little risk involved with having your blood taken. Veins and arteries vary in size from one person to another and from one side of the body to the other. Taking blood from some people may be more difficult than from others.Other risks:Excessive bleeding Fainting or feeling lightheaded Multiple punctures to locate veins Hematoma (blood accumulating under the skin) Infection (a slight risk any time the skin is broken)Open ReferencesReferencesBryant AE, Stevens DL. Streptococcus pyogenes. In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 9th ed. Philadelphia, PA: Elsevier; 2020:chap 197.AllVideoImagesTogBlood test - illustration Blood is drawn from a vein (venipuncture), usually from the inside of the elbow or the back of the hand. A needle is inserted into the vein, and the blood is collected in an air-tight vial or a syringe. Preparation may vary depending on the specific test.Blood testillustrationBlood test - illustration Blood is drawn from a vein (venipuncture), usually from the inside of the elbow or the back of the hand. A needle is inserted into the vein, and the blood is collected in an air-tight vial or a syringe. Preparation may vary depending on the specific test.Blood testillustration Tests for Anti-DNase B blood test Anti-DNase B blood testRelated Information Antibody(Special Topic)Antigen(Special Topic)Rheumatic fever(Condition)Poststreptococcal glomerulonephritis (GN)(Condition) Review Date: 5/19/2023 Reviewed By: Jatin M. Vyas, MD, PhD, Associate Professor in Medicine, Harvard Medical School; Associate in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, MA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. 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Anti-DNase B blood testStrep throat - anti-DNase B test; Antideoxyribonuclease B titer; ADN-B testAnti-DNase B is a blood test to look for antibodies to a substance (protein) produced by group A streptococcus. This is the bacteria that cause strep throat.Strep throatStrep throat is a disease that causes a sore throat (pharyngitis). It is an infection with a bacteria called group A streptococcus.ImageRead Article Now Book Mark Article When used together with the ASO titer test, more than 90% of past streptococcal infections can be identified.ASO titer testAntistreptolysin O (ASO) titer is a blood test to measure antibodies against streptolysin O, a substance produced by group A streptococcus bacteria. ...ImageRead Article Now Book Mark Article How the Test is Performed A blood sample is needed.Blood sample is neededVenipuncture is the collection of blood from a vein. It is most often done for laboratory testing.ImageRead Article Now Book Mark Article How to Prepare for the Test No special preparation is necessary. How the Test will Feel When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging sensation. Afterward, there may be some throbbing or a slight bruise. This soon goes away. Why the Test is Performed This test is most often done to tell if you have previously had a strep infection and if you might have rheumatic fever or kidney problems (glomerulonephritis) due to that infection.Rheumatic feverRheumatic fever is a disease that may develop after an infection with group A streptococcus bacteria (such as strep throat or scarlet fever). It can...Read Article Now Book Mark Article GlomerulonephritisGlomerulonephritis is a type of kidney disease in which the part of your kidneys that helps filter waste and fluids from the blood is damaged....ImageRead Article Now Book Mark Article Normal Results A negative test is normal. Some people have low concentrations of antibodies, but they have not had a recent strep infection. Therefore, normal values in different age groups are:Adults: less than 85 units/milliliter (mL) School-age children: less than 170 units/mL Preschool children: less than 60 units/mLNormal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different specimens. Talk to your health care provider about the meaning of your specific test results. What Abnormal Results Mean Increased levels of DNase B levels indicate exposure to group A streptococcus. Risks There is little risk involved with having your blood taken. Veins and arteries vary in size from one person to another and from one side of the body to the other. Taking blood from some people may be more difficult than from others.Other risks:Excessive bleeding Fainting or feeling lightheaded Multiple punctures to locate veins Hematoma (blood accumulating under the skin) Infection (a slight risk any time the skin is broken)Open ReferencesReferencesBryant AE, Stevens DL. Streptococcus pyogenes. In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 9th ed. Philadelphia, PA: Elsevier; 2020:chap 197.